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Human TNFSF12 / TWEAK Protein (Recombinant) - LS-G27201

Catalog Size Price
LS-G27201-10 10 µg Unavailable
LS-G27201-50 50 µg Unavailable
LS-G27201-1 1 mg Unavailable

Most Popular TNFSF12 / TWEAK Proteins

Human TNFSF12 / TWEAK Protein (Recombinant) - LS-G330
E. coli Expression System
154 AA
None
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.1 ng/µg of protein (less than 1EU/µg).
Human TNFSF12 / TWEAK Protein (Recombinant) - LS-G3685
E. coli Expression System
154 AA
None
Purified / Lyophilized / Biologically Active / Animal-Free / Endotoxin Level: Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
Human TNFSF12 / TWEAK Protein (Recombinant His) (aa148-247) - LS-G15405
E. coli Expression System
His
Purified / Lyophilized
Mouse TNFSF12 / TWEAK Protein (Recombinant 6His,N-terminus) (aa53-249) - LS-G25391
E. coli Expression System
6His,N-terminus
Lyophilized
Human TNFSF12 / TWEAK Protein (Recombinant) - LS-G27201
Hamster-Chinese CHO Cells
151 AA
None
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.2 EU/µg protein (determined by LAL method).

100% Guaranteed
LS-G27201
Recombinant Protein
TNFSF12 / TWEAK
Human
20-22 kDa (SDS-PAGE)
TWEAK, short for TNF-related weak inducer of apoptosis, is also known as TNFSF12 and DR3LG. It is a type II transmembrane protein belonging to the TNF superfamily. It is expressed widely in many tissues, such as the heart, skeletal muscle, spleen and peripheral blood. Binding of TWEAK to its receptor TWEAKR induces NF-?B activation, chemokine secretion and apoptosis in certain cell types. TWEAK has also been reported to promote endothelial cell proliferation and migration, thus serving as a regulator of angiogenesis.
RKTRARRAIA AHYEVHPRPG QDGAQAGVDG TVSGWEEARI
NSSSPLRYNR QIGEFIVTRA GLYYLYCQVH FDEGKAVYLK
LDLLVDGVLA LRCLEEFSAT AASSLGPQLR LCQVSGLLAL
RPGSSLRIRT LPWAHLKAAP FLTYFGLFQV H
CHO Cells
Hamster-Chinese
None
Greater than 95% by SDS-PAGE and HPLC
ED50 < 1 ng/ml, measured in a cell cytotoxicity assay using HTB-38 (HT-29) cells.
Less than 0.2 EU/µg protein (determined by LAL method).
Lyophilized from PBS.
Reconstitute in ddH2O or PBS at 100 µg/ml.
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
For research use only.

About TNFSF12 / TWEAK

O43508 NM_003809 NP_003800.1

TNFSF12 Protein, APO3/DR3 ligand Protein, APO3L Protein, DR3LG Protein, APO3 ligand Protein, TWEAK Protein

TNFSF12 / TWEAK is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner.

Requested From: 
Date Requested: 5/23/2018

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