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Human TNFRSF1B / TNFR2 Protein (Met1-Gly258) - LS-G51466

Catalog Size Price
LS-G51466-50 50 µg Unavailable
LS-G51466-100 100 µg Unavailable

Most Popular TNFRSF1B / TNFR2 Proteins

Human TNFRSF1B / TNFR2 Protein (Recombinant) - LS-G340
E. coli Expression System
174 AA
None
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.1 ng/µg of protein (less than 1EU/µg).
Human TNFRSF1B / TNFR2 Protein (Recombinant) - LS-G4431
E. coli Expression System
185 AA
None
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.1 ng/µg of protein.
Mouse TNFRSF1B / TNFR2 Protein (Recombinant His) (aa303-474) - LS-G13931
E. coli Expression System
His
Purified / Lyophilized
Human TNFRSF1B / TNFR2 Protein (Recombinant) - LS-G17132
E. coli Expression System
None
Purified / Lyophilized
Human TNFRSF1B / TNFR2 Protein (Recombinant Fc,C-terminus) (Leu23-Asp257) - LS-G40250
Human Human Cells
473 AA
Fc,C-terminus
Purified / Lyophilized / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).

100% Guaranteed
LS-G51466
TNFRSF1B / TNFR2
Human
Met 1-Gly 258
None
Greater than 97% by SDS-PAGE
Measured by its ability to inhibit TNFa-mediated cytotoxicity in L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 1-3 µg/mL in the presence of 0.1 ng/mL of recombinant mouse TNFa.
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from sterile PBS, pH 7.4
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
For research use only.

About TNFRSF1B / TNFR2

P20333 NM_001066 NP_001057.1

TNFRSF1B Protein, CD120b antigen Protein, CD120b Protein, Etanercept Protein, p75 TNF receptor Protein, Soluble TNFR1B variant 1 Protein, TNFBR Protein, Tumor necrosis factor receptor Protein, TNF-R-II Protein, TNF-R75 Protein, TNFR2 Protein, p75TNFR Protein, p80 TNF-alpha receptor Protein, TBPII Protein, TNF-R2 Protein, TNFR80 Protein, TNF-RII Protein, TNFR-II Protein, TNFR1B Protein

Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Requested From: 
Date Requested: 8/22/2017

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