Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Measured by its binding ability in a functional ELISA.Immobilized mouse HVEM-Fch (Cat:10567-M03H)at 10 µg/mL (100 µl/well) can bind biotinylated mouse BTLA-Fc,The EC50 of biotinylated mouse BTLA-Fc is 64-96 ng/mL.
Lyophilized PBS, pH 7.4
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
TNFRSF14 Protein, CD270 Protein, CD270 antigen Protein, CD40-like protein Protein, Herpesvirus entry mediator Protein, Herpesvirus entry mediator A Protein, HVEM Protein, LIGHTR Protein, Herpes virus entry mediator A Protein, TR2 Protein, ATAR Protein, HVEA Protein
HVEM (Herpes virus entry mediator) is a member of the tumor necrosis factor receptor family. This family of receptors plays a central role in the development of the immune system. HVEM has been shown to mediate HSV entry into activated T cells, in addition to modulating the activation of nuclear factor NF-kB (a transcriptional activator of multiple immuno modulatory and inflammatory genes) and transcription factor AP-1 (a regulator of cellular stress-response genes).