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Human TLR3 Recombinant Protein LS-G5017

Ordering

Wt. Vol. Conc. Price
10 µg - - $305
50 µg - - $860
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular TLR3 Proteins

Human TLR3 Recombinant Protein - LS-G5017
Human HEK 293 Cells
None
Unpurified / Endotoxin Level: Less than 0.1 ng/µg of protein (less than 1EU/µg).
Mouse TLR3 Recombinant (His) Protein - LS-G14596
E. coli Expression System
His
Unpurified
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Mouse TLR3 Recombinant (His + GST) Protein - LS-G14599
E. coli Expression System
His + GST
Unpurified
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

100% Guaranteed 100% Guaranteed
LS-G5017
Recombinant Protein
TLR3
Human
77.4 kDa
STTKCTVSHE VADCSHLKLT QVPDDLPTNI TVLNLTHNQL
RRLPAANFTR YSQLTSLDVG FNTISKLEPE LCQKLPMLKV
LNLQHNELSQ LSDKTFAFCT NLTELHLMSN SIQKIKNNPF
VKQKNLITLD LSHNGLSSTK LGTQVQLENL QELLLSNNKI
QALKSEELDI FANSSLKKLE LSSNQIKEFS PGCFHAIGRL
FGLFLNNVQL GPSLTEKLCL ELANTSIRNL SL
HEK 293 Cells
Human
None
Greater than 95% by SDS-PAGE
Determined by its ability to inhibit IL-8 secretion induced by Poly I:C in the TLR3 receptor-expressing HEK293 cells (HEK293 TLR3r). The ED50 for this effect is = 30 µg/ml in the presence of 100 µg/ml of Poly I:C.
Less than 0.1 ng/µg of protein (less than 1EU/µg).
Lyophilized from 20 mM sodium phosphate, pH 7.5
Centrifuge the vial before opening. Reconstitute in water to 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week.
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About TLR3

O15455 NM_003265 NP_003256.1

TLR3 Protein, CD283 Protein, Toll-like receptor 3 Protein, CD283 antigen Protein, IIAE2 Protein

TLR3 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.

Requested From: United States
Date Requested: 12/4/2016

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