Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
TJP2 Protein, C9DUPq21.11 Protein, DUP9q21.11 Protein, DFNA51 Protein, ZO-2 Protein, Zona occludens 2 Protein, Zonula occludens protein 2 Protein, Tight junction protein 2 Protein, Tight junction protein ZO-2 Protein, ZO2 Protein, X104 Protein, Zona occludens protein 2 Protein
TJP2 / ZO2 / ZO-2 is a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51.