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Human TDG / Thymine DNA Glycosylase Recombinant (His) Protein LS-G1923

Ordering

Wt. Vol. Conc. Price
100 µg - - $315
500 µg - - $680
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TDG / Thymine DNA Glycosylase Proteins

Human TDG / Thymine DNA Glycosylase Recombinant (His) Protein - LS-G1923
E. coli Expression System
His
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human TDG / Thymine DNA Glycosylase Recombinant (His) Protein - LS-G17868
E. coli Expression System
His
Unpurified / Lyophilized
Human TDG / Thymine DNA Glycosylase Recombinant (GST) Protein - LS-G30661
Wheat Wheat Germ Extract
GST
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

100% Guaranteed 100% Guaranteed
LS-G1923
Recombinant Protein
TDG / Thymine DNA Glycosylase
Human
MGSSHHHHHH SSGLVPRGSH MGSMEAENAG SYSLQQAQAF
YTFPFQQLMA EAPNMAVVNE QQMPEEVPAP APAQEPVQEA
PKGRKRKPRT TEPKQPVEPK KPVESKKSGK SAKSKEKQEK
ITDTFKVKRK VDRFNGVSEA ELLTKTLPDI LTFNLDIVII
GINPGLMAAY KGHHYPGPGN HFWKCLFMSG LSEVQLNHMD
DHTLPGKYGI GFTNMVERTT PGSKDLSSKE FREGGRILVQ
KLQKYQPRIA VFNGKCIYEI FSKEVFGVKV KNLEFGLQPH
KIPDTETLCY GMPSSSARCA QFPRAQDKVH YYIKLKDLRD
QLKGIERNMD VQEVQYTFDL QLAQEDAKKM AVKEEKYDPG
YEAAYGGAYG ENPCSSEPCG FSSNGLIESV ELRGESAFSG
IPNGQWMTQS FTDQIPSFSN HCGTQEQEEE SHA
E. coli
E. coli
His
Greater than 90% by SDS-PAGE
20 mM Tris-HCl, pH 8.0, 0.1 M NaCl, 0.4 M urea, 10% glycerol
For research use only.

About TDG / Thymine DNA Glycosylase

Q13569 NM_003211 NP_003202.3

TDG Protein, Thymine-DNA glycosylase Protein, Thymine DNA Glycosylase Protein

DNA glycosylase that plays a key role in active DNA demethylation: specifically recognizes and binds 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) in the context of CpG sites and mediates their excision through base-excision repair (BER) to install an unmethylated cytosine. Cannot remove 5-hydroxymethylcytosine (5hmC). According to an alternative model, involved in DNA demethylation by mediating DNA glycolase activity toward 5-hydroxymethyluracil (5hmU) produced by deamination of 5hmC.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
 
 

Requested From: United States
Date Requested: 12/11/2016

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