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| Catalog Number | Size | Price |
|---|---|---|
| LS-G137459-20 | 20 µg | $364 |
| LS-G137459-100 | 100 µg | $500 |
| LS-G137459-1 | 1 mg | $1,679 |
Human SYNGAP Protein (Recombinant 6His, N-terminus) - LS-G137459
Human SYNGAP Protein (Recombinant 6His, N-terminus) - LS-G137459
Description:
SYNGAP Protein LS-G137459 is a Recombinant Human SYNGAP produced in E. coli 1161-1343aa with 6His, N-terminus tag(s). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
SYNGAP Protein LS-G137459 is a Recombinant Human SYNGAP produced in E. coli 1161-1343aa with 6His, N-terminus tag(s). For Research Use Only
Specifications
Type
Recombinant Protein
Target
SYNGAP
Synonyms
SYNGAP1 | KIAA1938 | MRD5 | SYNGAP | Synaptic Ras-GAP 1 | Neuronal RasGAP | RASA5
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Tag
6His, N-terminus
Region
1161-1343aa
Predicted Molecular Weight
25.5 kDa
AA Sequence
MPHLSADIESAHIEREEYKLKEYSKSMDESRLDRVKEYEEEIHSLKERLHMSNRKLEEYERRLLSQEEQTSKILMQYQARLEQSEKRLRQQQAEKDSQIKSIIGRLMLVEEELRRDHPAMAEPLPEPKKRLLDAQERQLPPLGPTNPRVTLAPPWNGLAPPAPPPPPRLQITENGEFRNTADH
Expression System
E. coli
Source Species
E. coli
Purification
Greater than 90% by SDS-PAGE
Usage Summary
Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity).
Bio-Activity
Not Tested
Endotoxin
Not Tested
Presentation
Lyophilized from Tris, 50% Glycerol
Storage
Store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About SYNGAP
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Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/28/2024
Date Requested: 4/28/2024
