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Human SUFU Recombinant (His) Protein LS-G20335

Ordering

Wt. Vol. Conc. Price
5 µg - - $195
20 µg - - $255
1 mg - - $2,850
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular SUFU Proteins

Human SUFU Recombinant (His) Protein - LS-G1440
E. coli Expression System
His
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human SUFU Recombinant (His) Protein - LS-G20335
E. coli Expression System
His
Unpurified / Lyophilized
Human SUFU Recombinant (GST) Protein - LS-G33869
Wheat Wheat Germ Extract
GST
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

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LS-G20335
Recombinant Protein
SUFU
Human
56.1 kDa
SUFU Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 504 amino acids (1-484 a.a.) and having a molecular mass of 56.1kDa.SUFU is fused to a 20 amino acid His-tag at N-terminus and purified by proprietary chromatographic techniques.
E. coli
E. coli
His
Greater than 90% by SDS-PAGE
20 mM Tris-HCl, pH 8.0, 20 mM DTT, 10% glycerol, 20 mM NaCl.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About SUFU

Q9UMX1 NM_016169 NP_057253.2

SUFU Protein, SUFUXL Protein, PRO1280 Protein, SUFUH Protein, Suppressor of fused homolog Protein

Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling.

Requested From: United States
Date Requested: 12/8/2016

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