Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Measured by the ability of the immobilized protein to support the adhesion of HEK293 human embryonic kidney cells.When cells are added to coated plates(2µg/mL, 100µL/well), approximately 60% will adhere after 1 hour of incubation at 37?.
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from sterile PBS, pH 7.4
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
SPP1 Protein, BSPI Protein, BNSP Protein, Bone sialoprotein 1 Protein, ETA-1 Protein, Nephropontin Protein, OPN Protein, Secreted phosphoprotein 1 Protein, SPP-1 Protein, SPP1/CALPHA1 fusion Protein, Urinary stone protein Protein, Uropontin Protein, Osteopontin Protein, Bone sialoprotein I Protein
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.