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Human SHMT / SHMT1 Protein (Recombinant His) - LS-G17419
Purified / Lyophilized / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).
LS-G17419
Recombinant Protein
SHMT / SHMT1
Human
SHMT1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 503 amino acids (1-483 a.a.) and having a molecular mass of 55.2kDa.SHMT1 is fused to a 20 amino acid His-tag at N-terminus and purified by proprietary chromatographic techniques.
E. coli
E. coli
His
Greater than 95% by SDS-PAGE
Not Tested
Not Tested
20 mM Tris-HCl, pH 8.0, 20 mM NaCl, 20 mM DTT, 10% glycerol.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
SHMT1 Protein, 14 kDa protein Protein, CSHMT Protein, Serine methylase Protein, SHMT Protein
SHMT / SHMT1 is the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1.
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