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Human RSPO3 Recombinant (His) Protein LS-G5237

Ordering

Wt. Vol. Conc. Price
10 µg - - $345
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular RSPO3 Proteins

Human RSPO3 Recombinant Protein - LS-G4975
Hamster-Chinese CHO Cells
None
Unpurified / Endotoxin Level: Less than 0.1 ng/µg of protein (less than 1EU/µg).
Human RSPO3 Recombinant (His) Protein - LS-G19345
Human HEK 293 Cells
His
Unpurified
Human RSPO3 Recombinant (Fc + 6His,C-terminus) Protein - LS-G39369
Human Human Cells
Fc + 6His,C-terminus
Unpurified

100% Guaranteed 100% Guaranteed
LS-G5237
Recombinant Protein
RSPO3
Human
15.3 kDa. DTT-reduced protein migrates as 18 kDa and 24 kDa due to different glycosylation
HEK 293 Cells
Human
His
Greater than 95% by SDS-PAGE
Measured by its ability to induce activation of beta -catenin response in a Topflash Luciferase assay using HEK293T human embryonic kidney cells. The ED50 for this effect is typically 0.5 - 2.0 ng/ml in the presence of 5 ng/mL rmWnt-3a.
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from PBS, pH 7.4, mannitol or trehalose
Centrifuge the vial before opening. Reconstitute in sterile PBS, pH 7.4 to 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, store at -20°C.
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About RSPO3

Q9BXY4 NM_032784 NP_116173.2

RSPO3 Protein, CRISTIN1 Protein, HRspo3 Protein, HPWTSR Protein, R-spondin 3 Protein, Protein with TSP type-1 repeat Protein, R-spondin 3 homolog Protein, THSD2 Protein, PWTSR Protein, R-spondin-3 Protein, Roof plate-specific spondin-3 Protein

Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
 
 

Requested From: United States
Date Requested: 12/6/2016

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