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Human NBL1 / DAN Protein LS-G47319


Wt. Vol. Conc. Price
50 µg - - $335
100 µg - - $455
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)

Most Popular NBL1 / DAN Proteins

Human NBL1 / DAN Recombinant (His) Protein - LS-G2182
E. coli Expression System
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human NBL1 / DAN Recombinant (His) Protein - LS-G19041
E. coli Expression System
Unpurified / Lyophilized
Mouse NBL1 / DAN Recombinant (6His,C-terminus) Protein - LS-G40121
Human Human Cells

100% Guaranteed 100% Guaranteed
Met 1-Asp 180
Greater than 98% by SDS-PAGE
Measured by its ability to inhibit BMP4-induced activity in MC3T3-E1 Mouse osteoblastic cells. The ED50 for this effect is typically 5-20 µg/ml in the presence of 50 ng/mL of recombinant human BMP4.
Lyophilized PBS, pH 7.4
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
For research use only.

About NBL1 / DAN

P41271 NM_005380 NP_005371.2

NBL1 Protein, DAN domain family member 1 Protein, DAN Protein, DAND1 Protein, D1S1733E Protein, NB Protein, NO3 Protein, Zinc finger protein DAN Protein, Protein N03 Protein

NB / NBL1 is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development.

Requested From: United States
Date Requested: 10/21/2016

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