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Human MDM4 / MDMX Recombinant (GST) Protein LS-G29299

Ordering

Wt. Vol. Conc. Price
10 µg - - $415
Inquire for larger quantities
LSBio (USA Sales Only) LSBio (USA Sales Only)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MDM4 / MDMX Proteins

Human MDM4 / MDMX Recombinant (GST) Protein - LS-G29299
Wheat Wheat Germ Extract
GST
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
E. coli MDM4 / MDMX Protein - LS-G50561
None
Unpurified

100% Guaranteed 100% Guaranteed
LS-G29299
Recombinant Protein
MDM4 / MDMX
Human
81.3 kDa
MTSFSTSAQC STSDSACRIS PGQINQVRPK LPLLKILHAA
GAQGEMFTVK EVMHYLGQYI MVKQLYDQQE QHMVYCGGDL
LGELLGRQSF SVKDPSPLYD MLRKNLVTLA TATTDAAQTL
ALAQDHSMDI PSQDQLKQSA EESSTSRKRT TEDDIPTLPT
SEHKCIHSRE DEDLIENLAQ DETSRLDLGF EEWDVAGLPW
WFLGNLRSNY TPRSNGSTDL QTNQDVGTAI VSDTTDDLWF
LNESVSEQLG VGIKVEAADT EQTSEEVGKV SDKKVIEVGK
NDDLEDSKSL SDDTDVEVTS EDEWQCTECK KFNSPSKRYC
FRCWALRKDW YSDCSKLTHS LSTSDITAIP EKENEGNDVP
DCRRTISAPV VRPKDAYIKK ENSKLFDPCN SVEFLDLAHS
SESQETISSM GEQLDNLSEQ RTDTENMEDC QNLLKPCSLC
EKRPRDGNII HGRTGHLVTC FHCARRLKKA GASCPICKKE
IQLVIKVFIA
Wheat Germ Extract
Wheat
GST
Glutathione Sepharose
50 mM Tris-HCl, pH 8.0, 10 mM reduced glutathione
Store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About MDM4 / MDMX

O15151 NM_002393 NP_002384.2

MDM4 Protein, Mdm2-like p53-binding protein Protein, MDMX Protein, HDMX Protein, MRP1 Protein, p53-binding protein Mdm4 Protein, Protein Mdm4 Protein, Double minute 4 protein Protein, MDM4-related protein 1 Protein, Protein Mdmx Protein

MDM4 / MDMX is a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
12.5% SDS-PAGE of human MDM4 stained with Coomassie Blue
 

Requested From: United States
Date Requested: 12/4/2016

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