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| Catalog Number | Size | Price |
|---|---|---|
| LS-G137430-20 | 20 µg | $323 |
| LS-G137430-100 | 100 µg | $420 |
| LS-G137430-1 | 1 mg | $1,355 |
Human KMO Protein (Recombinant 10His, N-terminus) (Full Length) - LS-G137430
Human KMO Protein (Recombinant 10His, N-terminus) (Full Length) - LS-G137430
Description:
KMO Protein LS-G137430 is a Recombinant Human KMO produced in E. coli 1-486aa with 10His, N-terminus tag(s). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
KMO Protein LS-G137430 is a Recombinant Human KMO produced in E. coli 1-486aa with 10His, N-terminus tag(s). For Research Use Only
Specifications
Type
Recombinant Protein
Target
KMO
Synonyms
KMO | DJ317G22.1 | Kynurenine 3-hydroxylase | Kynurenine 3-monooxygenase
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Tag
10His, N-terminus
Region
1-486aa
Predicted Molecular Weight
61.9 kDa
AA Sequence
MDSSVIQRKKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDTRVATFTRGRSINLALSHRGRQALKAVGLEDQIVSQGIPMRARMIHSLSGKKSAIPYGTKSQYILSVSRENLNKDLLTAAEKYPNVKMHFNHRLLKCNPEEGMITVLGSDKVPKDVTCDLIVGCDGAYSTVRSHLMKKPRFDYSQQYIPHGYMELTIPPKNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCTLFMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKSHCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAISDLSMYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHWQKKVINKGLFFLGSLIAISSTYLLIHYMSPRSFLRLRRPWNWIAHFRNTTCFPAKAVDSLEQISNLISR
Expression System
E. coli
Source Species
E. coli
Purification
Greater than 85% by SDS-PAGE
Usage Summary
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
Bio-Activity
Not Tested
Endotoxin
Not Tested
Presentation
Lyophilized from Tris, 50% Glycerol
Storage
Store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About KMO
Publications (0)
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Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/28/2024
Date Requested: 4/28/2024
