Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Recombinant KIR3DL1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 132 amino acids and having a molecular mass of 15 kDa.The KIR3DL1 is purified by proprietary chromatographic techniques.
Greater than 95% by SDS-PAGE and HPLC
25 mM Tris-HCl, pH 7.5, 25 mM NaCl.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
KIR3DL1 Protein, AMB11 Protein, CD158E1 Protein, CD158e antigen Protein, CD158E Protein, CD158e1/2 Protein, CD158e2 Protein, Cl-11 Protein, KIR antigen 3DL1 Protein, MHC class I NK cell receptor Protein, NK-receptor Protein, NKB1 Protein, KIR Protein, KIR3DL1/S1 Protein, NKB1B Protein, Cl-2 Protein, Killer Ig receptor Protein, NKAT-3 Protein, NKAT3 Protein, p70 NK receptor CL-2/CL-11 Protein
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2).