Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Fully biologically active when compared to standard. The specific activity is determined by its binding ability in a functional ELISA. Immobilized rHuIL-36? at 1 µg/mL can bind recombinant human IL-1 Rrp2 Fc Chimera with a range of 0.15-5 µg/mL.
Tris buffer, 50% glycerol.
Reconstitute in sterile distilled water to 0.1-1 mg/ml.
Long term: -80°C; Short term: -20°C. Avoid freeze-thaw cycles.
IL36G Protein, IL-1 related protein 2 Protein, IL-1-related protein 2 Protein, IL-1RP2 Protein, IL-1(EPSILON) Protein, IL1E Protein, IL1F9 Protein, Interleukin-1 epsilon Protein, Interleukin-36 gamma Protein, IL-1F9 Protein, IL1H1 Protein, Interleukin 1 family, member 9 Protein, Interleukin-1 homolog 1 Protein, IL-1 epsilon Protein, IL-1-epsilon Protein, IL-1H1 Protein, IL1RP2 Protein, Interleukin 36, gamma Protein, Interleukin-1 family member 9 Protein
Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP.