Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.01 EU/µg protein (determined by LAL method).
Greater than 95% by SDS-PAGE and HPLC
Fully biologically active when compared to standard. The specific activity is determined by its binding ability in a functional ELISA. Immobilized rHuIL-36? at 1 µg/mL can bind recombinant human IL-1 Rrp2 Fc Chimera with a range of 0.15-5 µg/mL.
Tris buffer, 50% glycerol.
Reconstitute in sterile distilled water to 0.1-1 mg/ml.
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
IL36G Protein, IL-1 related protein 2 Protein, IL-1-related protein 2 Protein, IL-1RP2 Protein, IL-1(EPSILON) Protein, IL1E Protein, IL1F9 Protein, Interleukin-1 epsilon Protein, Interleukin-36 gamma Protein, IL-1F9 Protein, IL1H1 Protein, Interleukin 1 family, member 9 Protein, Interleukin-1 homolog 1 Protein, IL-1 epsilon Protein, IL-1-epsilon Protein, IL-1H1 Protein, IL1RP2 Protein, Interleukin 36, gamma Protein, Interleukin-1 family member 9 Protein
Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP.