Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Purified / Lyophilized / Endotoxin Level: Less than 0.1 ng/µg of protein.
Human IFNL1 / IL29 Protein (Recombinant) - LS-G4855
Human HEK 293 Cells
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 1.0 EU/µg protein.
IFNL1 / IL29
29 and 35 kDa, monomer, glycosylated
HEK 293 Cells
Greater than 95% by SDS-PAGE
ED50 is typically 0.5 to 5 ng/mL. The specific activity was determined by the dose-dependent protection of the cytopathic effect on A549 cells (human lung adenocarcinoma epithelial cell line) that were challenged with encephalomyocarditis (EMC) virus.
Less than 1.0 EU/µg protein.
Lyophilized from PBS
Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
IFNL1 Protein, IL-29 Protein, IL29 Protein, Interferon, lambda 1 Protein
Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state.