Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Lyophilized from 0.2 µm filtered PBS, protease inhibitors.
Centrifuge the vial before opening. Reconstitute in sterile deionized water or PBS to 0.5-1 mg/ml.
Store lyophilized at -20°C. After reconstitution, aliquot and store at -80°C. Avoid freeze-thaw cycles.
For research use only.
About HSP90AA / HSP90 Alpha
In mammalian cells, there are two or more genes encoding cytosolic Hsp90 homologues, with the human Hsp90 alpha showing 85% sequence identity to Hsp90 beta. The alpha- and the beta-forms are thought to be the result of a gene duplication event that occurred millions of years ago. In humans there are three HSP90 alpha genes, HSP90AA1 and HSP90AA2, which are inducible, and HSP90AB, which is constitutively expressed. HSP90 alpha is located in the cytosol.