Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
GRIK2 Protein, BA487F5.1 Protein, GluR-6 Protein, Glur5-7 Protein, GLUR6 Protein, Glutamate receptor form A Protein, Glutamate receptor form B Protein, EAA4 Protein, Glutamate receptor form C Protein, GLR6 Protein, GLUK6 Protein, Glutamate receptor form E Protein, MRT6 Protein, GluK2 Protein, Glutamate receptor 6 Protein, Glutamate receptor form D Protein
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.