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Human GCK / Glucokinase Protein (Recombinant) - LS-G5486

Catalog Size Price
LS-G5486-10 10 µg Unavailable
LSBio (USA Sales Only) LSBio (USA Sales Only)

Most Popular GCK / Glucokinase Proteins

Human GCK / Glucokinase Protein (Recombinant His) - LS-G3456
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Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human GCK / Glucokinase Protein (Recombinant) - LS-G5486
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Human GCK / Glucokinase Protein (Recombinant) - LS-G5487
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Human GCK / Glucokinase Protein (Recombinant His) - LS-G18455
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Mouse GCK / Glucokinase Protein (Recombinant His + T7) (aa3-226) - LS-G24078
E. coli Expression System
His + T7

100% Guaranteed
Recombinant Protein
GCK / Glucokinase
53.1 kDa
E. coli
E. coli
Greater than 80% by SDS-PAGE
303 pmol/min/µg. One unit is defined as the amount of enzyme that will convert 1 pmol of NADP to NADPH at 30oC. Assay conditions: 25 mM HEPES, pH 7.5, 2 mM MgCl2, 1.0 mM DTT, 0.5 mM NADP, 2.0 mM ATP, 25 mM glucose, 100 µg/ml BSA, 20 units/ml glucose 6-phosphate dehydrogenase, and 10 nM human pancreatic glucokinase at 30°C for 30 min.
Not Tested
50 mM potassium phosphate, pH 7.4, 50 mM NaCl, 0.5 mM DTT, 0.5 mM EDTA, 25% glycerol
Store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About GCK / Glucokinase

P35557 NM_000162 NP_000153.1

GCK Protein, FGQTL3 Protein, Glucokinase Protein, HK IV Protein, HKIV Protein, Hexokinase d, liver isozymes Protein, Hexokinase-4 Protein, Hexokinase-D Protein, HXKP Protein, GLK Protein, Glucokinase (hexokinase 4) Protein, Hexokinase type IV Protein, HHF3 Protein, HK4 Protein, LGLK Protein, MODY2 Protein

Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion.

Requested From: 
Date Requested: 6/21/2018

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