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Human FASLG / Fas Ligand Protein (Recombinant His) - LS-G5227

Catalog Size Price
LS-G5227-10 10 µg Unavailable

Most Popular FASLG / Fas Ligand Proteins

Human FASLG / Fas Ligand Protein (Recombinant) - LS-G331
Hamster-Chinese CHO Cells
156 AA
None
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.1 ng/µg of protein (less than 1EU/µg).
Human FASLG / Fas Ligand Protein (Recombinant His) - LS-G2109
E. coli Expression System
173 AA
His
Purified
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human FASLG / Fas Ligand Protein (Recombinant DDK) (aa103-281) - LS-G3868
Human HEK 293 Cells
DDK
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.05 EU/µg protein (determined by LAL method).
Human FASLG / Fas Ligand Protein (Recombinant Human IgG1 Fc) (aa139-281) - LS-G3966
Human HEK 293 Cells
Human IgG1 Fc
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.01 EU/µg protein (determined by LAL method).
Oligomerization of FasL (h) efficiently triggers Jurkat cell death.Method: Jurkat cells were treated O/N with the indicated concentrations of MegaFasL, Soluble (human) (rec.) (rec.) (rec.) or FasL, Soluble (human) (rec.) + TNF ligands enhancer (2 fold-dilutions, first concentration of 1000ng/ml). Cell death was quantified using PMS/MTS. The oligomeric FasL recombinant proteins (MegaFasL, Soluble (human), Fc:FasL, Soluble (human) and FasL, Soluble (human) + TNF ligands enhancer) kill Jurkat cells at IC50 <0.2ng/ml.
Human FASLG / Fas Ligand Protein (Recombinant DDK + human ACRP30headless aa 18-111) (aa139-281) - LS-G3967
Human HEK 293 Cells
DDK + human ACRP30headless aa 18-111
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.02 EU/µg protein (determined by LAL method).
Oligomerization of FasL (h) efficiently triggers Jurkat cell death.Method: Jurkat cells were treated O/N with the indicated concentrations of FasL (human) (multimeric) (rec.) (rec.) (rec.) or FasL, Soluble (human) (rec.) + TNF ligands enhancer (2 fold-dilutions, first concentration of 1000ng/ml). Cell death was quantified using PMS/MTS. The oligomeric FasL recombinant proteins (FasL (human) (multimeric) (rec.), Fc:FasL, Soluble (human) and FasL, Soluble (human) + TNF ligands enhancer) kill Jurkat cells at IC50 <0.2ng/ml.

100% Guaranteed
LS-G5227
Recombinant Protein
FASLG / Fas Ligand
Human
17.7 kDa. Protein migrates as 25-32 kDa in reduced SDS-PAGE due to glycosylation
HEK 293 Cells
Human
His
Greater than 95% by SDS-PAGE
Measured by its ability to induce apoptosis of Jurkat human acute T cell leukemia cells. The ED50 for this effect is typically 0.1-1.5 ng/mL in the presence of 10 µg/mL of a crosslinking antibody Mouse Anti poly-Histidine Monoclonal Antibody.
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from 50 mM Tris, 100 mM glycine, pH 7.0, mannitol or trehalose
Centrifuge the vial before opening. Reconstitute in sterile PBS, pH 7.4 to 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, store at -20°C.
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About FASLG / Fas Ligand

P48023 NM_000639 NP_000630.1

FASLG Protein, ALPS1B Protein, Apoptosis antigen ligand Protein, APTL Protein, CD95L Protein, CD95 ligand Protein, CD178 antigen Protein, CD95-L Protein, Fas antigen ligand Protein, Fas ligand Protein, FASL Protein, TNFSF6 Protein, APT1LG1 Protein, CD178 Protein

Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
 

Requested From: 
Date Requested: 5/27/2018

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