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Human F2 / Prothrombin / Thrombin Recombinant (GST) Protein LS-G28412

Ordering

Wt. Vol. Conc. Price
10 µg - - $415
Inquire for larger quantities
LSBio (USA Sales Only) LSBio (USA Sales Only)
206-374-1102
866-206-6909
Orders@LSBio.com
 

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LS-G28412
Recombinant Protein
F2 / Prothrombin / Thrombin
Human
96.4 kDa
MAHVRGLQLP GCLALAALCS LVHSQHVFLA PQQARSLLQR
VRRANTFLEE VRKGNLEREC VEETCSYEEA FEALESSTAT
DVFWAKYTAC ETARTPRDKL AACLEGNCAE GLGTNYRGHV
NITRSGIECQ LWRSRYPHKP EINSTTHPGA DLQENFCRNP
DSSTTGPWCY TTDPTVRRQE CSIPVCGQDQ VTVAMTPRSE
GSSVNLSPPL EQCVPDRGQQ YQGRLAVTTH GLPCLAWASA
QAKALSKHQD FNSAVQLVEN FCRNPDGDEE GVWCYVAGKP
GDFGYCDLNY CEEAVEEETG DGLDEDSDRA IEGRTATSEY
QTFFNPRTFG SGEADCGLRP LFEKKSLEDK TERELLESYI
DGRIVEGSDA EIGMSPWQVM LFRKSPQELL CGASLISDRW
VLTAAHCLLY PPWDKNFTEN DLLVRIGKHS RTRYERNIEK
ISMLEKIYIH PRYNWRENLD RDIALMKLKK PVAFSDYIHP
VCLPDRETAA SLLQAGYKGR VTGWGNLKET WTANVGKGQP
SVLQVVNLPI VERPVCKDST RIRITDNMFC AGYKPDEGKR
GDACEGDSGG PFVMKSPFNN RWYQMGIVSW GEGCDRDGKY
GFYTHVFRLK KWIQKVIDQF GE
Wheat Germ Extract
Wheat
GST
Glutathione Sepharose
50 mM Tris-HCl, pH 8.0, 10 mM reduced glutathione
Store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About F2 / Prothrombin / Thrombin

P00734 NM_000506 NP_000497.1

F2 Protein, Prothrombin B-chain Protein, Coagulation factor II Protein, FACTOR II Protein, Prothrombin Protein, PT Protein, RPRGL2 Protein, Serine protease Protein, THPH1 Protein, Thrombin Protein

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Finally, peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
12.5% SDS-PAGE of human F2 stained with Coomassie Blue
 

Requested From: United States
Date Requested: 12/7/2016

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