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Human DKK1 Recombinant (His) Protein LS-G22313

Ordering

Wt. Vol. Conc. Price
50 µg - - $275
200 µg - - $475
500 µg - - $785
1000 µg - - $1,245
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular DKK1 Proteins

Human DKK1 Recombinant (His) Protein - LS-G19257
E. coli Expression System
His
Unpurified / Lyophilized
DKK1 Recombinant Protein - LS-G27007
Hamster-Chinese CHO Cells
None
Unpurified / Endotoxin Level: Less than 0.2 EU/µg protein (determined by LAL method).
Human DKK1 Recombinant Protein - LS-G27268
Hamster-Chinese CHO Cells
None
Unpurified / Endotoxin Level: Less than 0.2 EU/µg protein (determined by LAL method).

100% Guaranteed 100% Guaranteed
LS-G22313
Recombinant Protein
DKK1
Human
29.8 kD
aa 33-263
LNSVLNSNAI KNLPPPLGGA AGHPGSAVSA APGILYPGGN
KYQTIDNYQP YPCAEDEECG TDEYCASPTR GGDAGVQICL
ACRKRRKRCM RHAMCCPGNY CKNGICVSSD QNHFRGEIEE
TITESFGNDH STLDGYSRRT TLSSKMYHTK GQEGSVCLRS
SDCASGLCCA RHFWSKICKP VLKEGQVCTK HRRKGSHGLE
IFQRCYCGEG LSCRIQKDHH QASNSSRLHT CQRH
E. coli
E. coli
His
20 mM Tris, pH 8.0, 500 mM NaCl, 50% glycerol
Long term: -80°C; Short term: -20°C. Avoid freeze-thaw cycles.
For research use only.

About DKK1

O94907 NM_012242 NP_036374.1

DKK1 Protein, Dickkopf-1 like Protein, DKK-1 Protein, Dickkopf-1 Protein, Dickkopf-related protein 1 Protein, Dickkopf related protein-1 Protein, HDkk-1 Protein, Hdkk1 Protein, Dickkopf-like protein 1 Protein, SK Protein

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Requested From: United States
Date Requested: 12/10/2016

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