Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SPRR1B Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (a.a 2-89) containing 97 amino acids including a 9 a.a N-terminal His tag. The total molecular mass is 10.9kDa (calculated).
Greater than 95% by Densitometry
Lyophilized from 0.05 M phosphate buffer, 0.05 M NaCl, pH 7.4.
Store at -20°C lyophilized. Once reconstituted, aliquot to avoid freeze/thaw and store at -20°C.
SPRR1B Protein, 14.9 kd pancornulin Protein, 14.9 kDa pancornulin Protein, CORNIFIN Protein, GADD33 Protein, SPR-IB Protein, Small proline-rich protein IB Protein, SPRR1 Protein, Cornifin B Protein, Cornifin-B Protein, Small proline-rich protein 1B Protein
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.