Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CKMBITI Human Recombinant produced in Pichia Pastoris is a glycosylated polypeptide chain and a full length Creatine Kinase MB isoenzyme, which is missing the C-terminal Lysine on the M subunit. CKMBITI is a dimeric protein comprised of M and B subunits, having a total Mw of ~44kDa. The CKMBITI is purified by proprietary chromatographic techniques.
Greater than 95% by SDS-PAGE
0.02 M Potassium Phosphate, 0.02 M DTT, 50% glycerol, pH 5.0-6.0.
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.
About CKMB / Creatine Kinase MB
In the cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes: CK-MM, CK-BB and CK-MB. The genes for these subunits are located on different chromosomes: B on 14q32 and M on 19q13. In addition to those three cytosolic CK isoforms, there are two mitochondrial creatine kinase isoenzymes, the ubiquitous and sarcomeric form.