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Human CDKN2A / p16INK4a Protein (Recombinant TAT) - LS-G66

Catalog Size Price
LS-G66-5 5 µg Unavailable
LS-G66-25 25 µg Unavailable

Most Popular CDKN2A / p16INK4a Proteins

Human CDKN2A / p16INK4a Protein (Recombinant TAT) - LS-G66
E. coli Expression System
167 AA
TAT
Purified / Lyophilized / Endotoxin Level: Less than 0.1 ng/µg of protein (less than 1EU/µg).
Human CDKN2A / p16INK4a Protein (Recombinant) - LS-G67
E. coli Expression System
156 AA
None
Purified / Lyophilized / Endotoxin Level: Less than 0.1 ng/µg of protein (less than 1EU/µg).
Human CDKN2A / p16INK4a Protein (Recombinant His + T7) (aa8-156) - LS-G12847
E. coli Expression System
His + T7
Purified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Mouse CDKN2A / p16INK4a Protein (Recombinant His + T7) (aa3-154) - LS-G12848
E. coli Expression System
His + T7
Purified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Rat CDKN2A / p16INK4a Protein (Recombinant His + T7) (aa3-155) - LS-G12849
E. coli Expression System
His + T7
Purified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

100% Guaranteed
LS-G66
Recombinant Protein
CDKN2A / p16INK4a
Human
18 kDa
EPAAGSSMEP SADWLATAAA RGRVEEVRAL LEAGALPNAP
NSYGRRPIQV MMMGSARVAE LLLLHGAEPN CADPATLTRP
VHDAAREGFL DTLVVLHRAG ARLDVRDAWG RLPVDLAEEL
GHRDVARYLR AAAGGTRGSN HARIDAAEGP SDIPDGYGRK
KRRQRRR
E. coli
E. coli
TAT
Greater than 95% by SDS-PAGE and HPLC
Not Tested
Less than 0.1 ng/µg of protein (less than 1EU/µg).
Sterile filtered, lyophilized from 5 mM sodium citrate, pH 3.0, 100 mM sodium chloride, 0.5 mM DTT
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
If lyophilized, can be stored for 1 month at room temperature, 6 months at 4°C, or through the expiration date at -20°C to -80°C. Once reconstituted per the supplied instructions, can be stored for 3 months at -20°C to -80°C, or for 1 week at 2°C to 8°C. Avoid repeat freeze-thaw cycles.
For research use only.

About CDKN2A / p16INK4a

P42771 NM_000077 NP_000068.1

CDKN2A Protein, ARF Protein, Cdk4 inhibitor Protein, CDK4 inhibitor p16-INK4 Protein, INK4 Protein, INK4A Protein, Multiple tumor suppressor 1 Protein, MTS-1 Protein, MTS1 Protein, p16-INK4 Protein, p16-INK4A Protein, p16INK4 Protein, p19 Protein, p14 Protein, p16 Protein, p16 INK4A Protein, p16INK4A Protein, p14ARF Protein, TP16 Protein, CDK4I Protein, CDKN2 Protein, CMM2 Protein, MLM Protein, p19ARF Protein

Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes.

Requested From: 
Date Requested: 8/17/2017

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