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| Catalog Number | Size | Price |
|---|---|---|
| LS-G136293-25 | 25 µg (0.5 mg/ml) | $698 |
Human CD274 / B7-H1 / PD-L1 Protein (Recombinant) (Biotin) - LS-G136293
Human CD274 / B7-H1 / PD-L1 Protein (Recombinant) (Biotin) - LS-G136293
Description:
CD274 / B7-H1 / PD-L1 Protein LS-G136293 is a Recombinant Human CD274 / B7-H1 / PD-L1 produced in CHO Cells (Biotin) Murine CD8 alpha leader sequence, the mature extracellular domain of human CD274 fused to murine IgG. For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
CD274 / B7-H1 / PD-L1 Protein LS-G136293 is a Recombinant Human CD274 / B7-H1 / PD-L1 produced in CHO Cells (Biotin) Murine CD8 alpha leader sequence, the mature extracellular domain of human CD274 fused to murine IgG. For Research Use Only
Specifications
Type
Recombinant Protein
Target
CD274 / B7-H1 / PD-L1
Synonyms
CD274 | B7-H | B7 homolog 1 | B7-H1 | B7H1 | CD274 molecule | CD274 antigen | PDCD1 ligand 1 | PDL1 | PD-L1 | PDCD1L1 | PDCD1LG1 | Programmed death ligand 1
Species
Human
Modifications
Unmodified
Conjugations
Biotin.
Also available Unconjugated.
Region
Murine CD8 alpha leader sequence, the mature extracellular domain of human CD274 fused to murine IgG
Predicted Molecular Weight
54.4 kDa
AA Sequence
ftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlkvqhssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapynkinqrilvvdpvtseheltcqaegypkaeviwtssdhqvlsgkttttnskreeklfnvtstlrintttneifyctfrrldpeenhtaelvipelplahppnerthtr
Expression System
CHO Cells
Source Species
Hamster-Chinese
Usage Summary
A soluble fusion protein consisting of the murine CD8 alpha leader sequence, the mature extracellular (224aa) domain of human CD274 fused to murine IgG2a Fc + hinge (233aa). muCD8 apha signal peptide residual amino acids+ linker: (1)kpqapelrgsas, CD274 mature EC (224aa): (13)ftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlkvqhssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapynkinqrilvvdpvtseheltcqaegypkaeviwtssdhqvlsgkttttnskreeklfnvtstlrintttneifyctfrrldpeenhtaelvipelplahppnerthtr, Linker + Murine IgG2a Hinge + Fc (235 aa): (237)gteprgptikpcppckcpapnllggpsvfifppkikdvlmislspivtcvvvdvseddpdvqiswfvnnvevhtaqtqthredynstlrvvsalpiqhqdwmsgkefkckvnnkdlpapiertiskpkgsvrapqvyvlpppeeemtkkqvtltcmvtdfmpediyvewtnngktelnykntepvldsdgsyfmysklrvekknwvernsyscsvvheglhnhhttksfsrtpg(471). Predicted monomeric (non glycosylated) molecular weight: 54.4 kd. The molecule is dimeric and runs at about 120 kd in SDS-PAGE under native conditions. Purity of recombinant protein was >90% by SDS-PAGE. N-terminal sequence was as predicted: KPQAP. Biotinylated recombinant protein was active in EIA, binding to anti-CD274 mAbs ANC6H1, clone M1H1, and to recombinant CD279(PD1), using SA/HRP for detection.
Bio-Activity
Not Tested
Endotoxin
Not Tested
Presentation
50 mM Sodium Phosphate, pH 7.5, 150 mM NaCl, 100 mM KCl, 0.04% Sodium Azide, 5% Glycerol, 0.2% BSA
Storage
Store at 2°C to 5°C for up to 6 months. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CD274 / B7-H1 / PD-L1
Publications (0)
Customer Reviews (0)
Popular CD274 / B7-H1 / PD-L1 Proteins
Source:
E. coli
Tag:
His-GST
Source:
Human
Tag:
6His, C-terminus
Source:
E. coli
Tag:
His
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/6/2024
Date Requested: 5/6/2024
