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| Catalog Number | Size | Price |
|---|---|---|
| LS-G136894-20 | 20 µg | $854 |
| LS-G136894-100 | 100 µg | $1,293 |
Human CCR4 Protein (Recombinant 10His, N-terminus) (Full Length) - LS-G136894
Human CCR4 Protein (Recombinant 10His, N-terminus) (Full Length) - LS-G136894
Description:
CCR4 Protein LS-G136894 is a Recombinant Human CCR4 produced in E. coli 1-360aa with 10His, N-terminus tag(s). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
CCR4 Protein LS-G136894 is a Recombinant Human CCR4 produced in E. coli 1-360aa with 10His, N-terminus tag(s). For Research Use Only
Specifications
Type
Recombinant Protein
Target
CCR4
Synonyms
CCR4 | C-C chemokine receptor type 4 | CD194 | CD194 antigen | C-C CKR-4 | Chemr13 | CKR-4 | CC chemokine receptor 4 | CC-CKR-4 | CCR-4 | HGCN:14099 | C-c chemokine receptor 4 | Chemokine (C-C) receptor 4 | CKR4 | CMKBR4 | K5-5
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Tag
10His, N-terminus
Region
1-360aa
Predicted Molecular Weight
44.9 kDa
AA Sequence
MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGNSVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYLVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFSTCYTERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATETLAFVHCCLNPIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLHDAL
Expression System
E. coli
Source Species
E. coli
Purification
Greater than 85% by SDS-PAGE
Usage Summary
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Bio-Activity
Not Tested
Endotoxin
Not Tested
Presentation
Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
Briefly centrifuge vial prior to opening. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Add 5-50% of glycerol (final concentration).
Storage
Store lyophilized at -20°C or -80°C for up to 1 year. Once reconstituted: store undiluted at 4°C for up to 1 week. Aliquot and store undiluted at -20°C or -80°C for up to 6 months. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CCR4
Publications (0)
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Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/28/2024
Date Requested: 4/28/2024
