Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
1. Measured by its binding ability in a functional ELISA. 2. Immobilized human APOH-his at 2 µg/mL (100 µl/well) can bind biotinylated human LDLR-his, The EC50 of biotinylated human LDLR-his is 0.35 µg/mL.3.Immobilized human APOH-his at 2 µg/mL (100 µl/well) can bind biotinylated mouse LDLR-his, The EC50 of biotinylated mouse LDLR-his is 26 ng/mL.
Lyophilized PBS, pH 7.4
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
APOH Protein, Apo-H Protein, Anticardiolipin cofactor Protein, Apolipoprotein H Protein, B2GP1 Protein, B2GPI Protein, Beta-2-glycoprotein I Protein, APC inhibitor Protein, Beta(2)GPI Protein, BG Protein, B2G1 Protein, Beta-2-glycoprotein 1 Protein
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.