Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
GNAS Protein, AHO Protein, C20orf45 Protein, Extra large alphas protein Protein, GSP Protein, GNAS complex locus Protein, GNASXL Protein, NESP Protein, PHP1B Protein, PHP1C Protein, PHP1A Protein, POH Protein, SCG6 Protein, XLalphas Protein, GNAS1 Protein, GPSA Protein, GSA Protein, NESP55 Protein, Protein ALEX Protein, Secretogranin VI Protein
The GNAS1 gene encodes the alpha subunit of the G protein Gs, which couples receptor binding by several hormones to activation of adenylate cyclase (Hayward et al., 1998). This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons.