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Baculovirus MER / MERTK Protein (Glu578-Tyr872) - LS-G47973
Purified / Lyophilized / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).
LS-G47973
MER / MERTK
Baculovirus
Glu 578-Tyr 872
Baculovirus
Insect
None
Greater than 85% by SDS-PAGE
Kinase activity untested
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 0.3 mM DTT, 10% glycerol, ph 7.4.
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
MERTK Protein, Eyk Protein, MER Protein, MER receptor tyrosine kinase Protein, Nyk Protein, Proto-oncogene c-Mer Protein, RP38 Protein, STK kinase Protein, C-mer Protein, Receptor tyrosine kinase MerTK Protein, Tyrosine-protein kinase Mer Protein
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis). Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules.
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