Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
1. Immobilized Rhesus His-NKG2D (78-216) at 10 µg/ml (100 µl/well) can bind human ULBP1-Fch, The EC50 of human ULBP1-Fch is 0.12-0.28 µg/ml. 2. Immobilized Rhesus His-NKG2D (78-216) at 10 µg/ml (100 µl/well) can bind human MICB-Fch, The EC50 of human MICB-Fch is 33.8-79 ng/ml.
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 8.01.
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
KLRK1 Protein, D12S2489E Protein, CD314 antigen Protein, KLR Protein, NK cell receptor D Protein, NKG2D Protein, NKG2-D Protein, NKG2-D-activating NK receptor Protein, CD314 Protein
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.