Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
1. Kinase activity untested 2. Measured by its binding ability in a functional ELISA. Immobilized recombinant human FGFR1 (aa 311-731) at 10 µg/ml (100 µl/well) can bind biotinylated human FGF acidic with a linear range of 15.6-250 ng/ml. 2. Measured by its binding ability in a functional ELISA. Immobilized recombinant human FGFR1 (aa 311-731) at 10 µg/ml (100 µl/well) can bind biotinylated human FGF basic with a linear range of 0.16-2.5 µg/ml.
Supplied as sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 20% glycerol, 0.3 mM DTT.
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB.