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Human ERN1 / IRE1 Protein (Recombinant His + GST) (Pro465-Leu977) - LS-G47849

Catalog Size Price
LS-G47849-20 20 µg Unavailable
LS-G47849-50 50 µg (0.28 mg/ml) Unavailable

Most Popular ERN1 / IRE1 Proteins

Human ERN1 / IRE1 Protein (Recombinant His + T7) (aa571-832) - LS-G24872
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Human ERN1 / IRE1 Protein (Recombinant GST) - LS-G28385
Wheat Wheat Germ Extract
70 AA
12.5% SDS-PAGE of human ERN1 stained with Coomassie Blue
Human ERN1 / IRE1 Protein (Recombinant His + GST) (Pro465-Leu977) - LS-G47849
Baculovirus Sf21 Cells
His + GST
Purified / Biologically Active / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).
Human ERN1 / IRE1 Protein (Recombinant GST,N-terminus) (aa401-500) - LS-G58488
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100 AA
12.5% SDS-PAGE Stained with Coomassie Blue.
Human ERN1 / IRE1 Protein (Recombinant Myc + DDK) - LS-G70861
Human HEK 293 Cells
1029 AA
Myc + DDK

100% Guaranteed
Recombinant Protein
Pro 465-Leu 977
Sf21 Cells
His + GST
Greater than 80% by SDS-PAGE
1. Kinase activity untested 2. Measured by its nuclease activity to cleave Xbp1 single stem-loop mini-substrate.
Less than 1.0 EU/µg protein (determined by LAL method).
Supplied as sterile 20 mM Tris, 500 mM NaCl, 10% glycerol, ph 7.4.
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
For research use only.

About ERN1 / IRE1

O75460 NM_001433 NP_001424.3

ERN1 Protein, ER to nucleus signalling 1 Protein, Inositol-requiring enzyme 1 Protein, Inositol-requiring protein 1 Protein, Ire1-alpha Protein, IRE1a Protein, HIRE1p Protein, IRE1 Protein, Inositol-requiring 1 Protein, IRE1P Protein

The endoribonuclease IRE1/ERN1 encodes the ER-to-nucleus signaling 1 protein, a human homolog of the yeast Ire1 gene product. In S. cerevisiae, as well as in human, this ER transmembrane IRE serine/threonine protein kinase monitors the status of unfolded proteins inside the ER lumen in response to stress. Activation of ERN1 leads to oligomerization, autophosphorylation, and proteolytic cleavage.

Requested From: 
Date Requested: 5/26/2018

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