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Baculovirus CHEK1 / CHK1 Protein (Met1-Thr476) - LS-G47848

Catalog Size Price
LS-G47848-20 20 µg Unavailable
LS-G47848-50 50 µg Unavailable

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100% Guaranteed
LS-G47848
CHEK1 / CHK1
Baculovirus
Met1-Thr476
Baculovirus
Insect
None
Greater than 95% by SDS-PAGE
The specific activity was determined to be 32 nmol/min/mg using CHKtide peptide (KKKVSRSGLYRSPSMPENLNRPR) as substrate.
Less than 1.0 EU/µg protein (determined by LAL method).
Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10% glycerol, 2 mM Glutathione.
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
For research use only.

About CHEK1 / CHK1

O14757 NM_001274 NP_001265.2

CHEK1 Protein, CHK1 checkpoint homolog Protein, Cell cycle checkpoint kinase Protein, Checkpoint kinase 1 Protein, CHK1 Protein, Chk1-S Protein, Protein kinase chk1 Protein, Checkpoint kinase-1 Protein

Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. This regulation is achieved by a number of mechanisms that together help to preserve the integrity of the genome. Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to and phosphorylates CDC25A, CDC25B and CDC25C.

Requested From: 
Date Requested: 12/12/2017

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