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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A8597-50 50 µg (1 mg/ml) $425 
VRL1 / TRPV2 Antibody - Anti-TRPV2 antibody IHC of human dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
VRL1 / TRPV2 Antibody - Brain, Alzheimer's Disease neurons and glia
VRL1 / TRPV2 Antibody - Brain, Cortex, Neurons and glia
VRL1 / TRPV2 Antibody - Anti-VRL1 / TRPV2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
VRL1 / TRPV2 Antibody - Anti-VRL1 / TRPV2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
VRL1 / TRPV2 Antibody - Anti-VRL1 / TRPV2 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
VRL1 / TRPV2 Antibody - Anti-TRPV2 antibody IHC of human dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
VRL1 / TRPV2 Antibody - Brain, Alzheimer's Disease neurons and glia
VRL1 / TRPV2 Antibody - Brain, Cortex, Neurons and glia
VRL1 / TRPV2 Antibody - Anti-VRL1 / TRPV2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
VRL1 / TRPV2 Antibody - Anti-VRL1 / TRPV2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
VRL1 / TRPV2 Antibody - Anti-VRL1 / TRPV2 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus Neuro PathPlus™ VRL1 / TRPV2 Antibody N‑Terminus Polyclonal IHC LS‑A8597

PathPlus Neuro PathPlus™ VRL1 / TRPV2 Antibody N‑Terminus Polyclonal IHC LS‑A8597

Note: This antibody replaces LS-C92318, LS-C56787
Antibody:
Rabbit Polyclonal to Human VRL1 / TRPV2
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Horse, Pig
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A8597-50
50 µg
1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human VRL1 / TRPV2
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Horse, Pig
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Transient Receptor Potential cation channel, subfamily V, member 2 (TRPV2) is a transient receptor potential ion channel that responds to high-threshold noxious heat (with a threshold of approximately 52 degrees C), but neither to capsaicin nor to proton. TRPV2 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. It has been proposed that responses to noxious heat involve these related, but distinct, ion-channel subtypes that together detect a range of stimulus intensities. The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human VRL1 / TRPV2
Host
Rabbit
Reactivity
Human, Monkey, Horse, Pig (tested or 100% immunogen sequence identity)
Predicted
Bovine, Hamster, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 15 amino acid peptide from N-terminus of human TRPV2. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Horse, Pig (100%); Gibbon, Bovine, Hamster, Panda, Rabbit (93%); Mouse, Dog (87%); Elephant (80%).
Blocking Peptide
LS-E29443 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A8597. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human TRPV2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Usage
Immunohistochemistry: The unconjugated form was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for the unconjugated form was determined to be 10 ug/ml.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About VRL1 / TRPV2
Q9Y5S1 NM_016113 NP_057197.2

Validation

VRL1 / TRPV2 Antibody - Anti-TRPV2 antibody IHC of human dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TRPV2 antibody IHC of human dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PathPlus™ Validated
Anti-TRPV2 antibody IHC of human dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

VRL1 / TRPV2 Antibody - Brain, Alzheimer's Disease neurons and glia
Brain, Alzheimer's Disease neurons and glia
PathPlus™ Validated
Brain, Alzheimer's Disease neurons and glia

VRL1 / TRPV2 Antibody - Brain, Cortex, Neurons and glia
Brain, Cortex, Neurons and glia
PathPlus™ Validated
Brain, Cortex, Neurons and glia

VRL1 / TRPV2 Antibody - Anti-VRL1 / TRPV2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-VRL1 / TRPV2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PathPlus™ Validated
Anti-VRL1 / TRPV2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

VRL1 / TRPV2 Antibody - Anti-VRL1 / TRPV2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-VRL1 / TRPV2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PathPlus™ Validated
Anti-VRL1 / TRPV2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

VRL1 / TRPV2 Antibody - Anti-VRL1 / TRPV2 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-VRL1 / TRPV2 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PathPlus™ Validated
Anti-VRL1 / TRPV2 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
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CD79A / CD79 Alpha Antibody - Anti-CD79A antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
Species: Human, Mouse, Rat, Bovine, Guinea pig, Opossum, Rabbit, Chicken, Equine, Porcine
Applications: IHC, IHC - Paraffin, IHC - Frozen, Flow Cytometry

Requested From: United States
Date Requested: 10/23/2019