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Catalog Number Size Price
LS-A1288-50 50 µg (0.6 mg/ml) $460 
TACR2 / NK2R Antibody - Breast, Carcinoma
TACR2 / NK2R Antibody - Ovary, carcinoma
TACR2 / NK2R Antibody - Skin, Malignant Melanoma
TACR2 / NK2R Antibody - Anti-TACR2 / Nk2 / NK2R antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TACR2 / NK2R Antibody - Anti-Neurokinin A Receptor antibody IHC of human small intestine, muscularis propria. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TACR2 / NK2R Antibody - Anti-TACR2 / Nk2 / NK2R antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TACR2 / NK2R Antibody - Breast, Carcinoma
TACR2 / NK2R Antibody - Ovary, carcinoma
TACR2 / NK2R Antibody - Skin, Malignant Melanoma
TACR2 / NK2R Antibody - Anti-TACR2 / Nk2 / NK2R antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TACR2 / NK2R Antibody - Anti-Neurokinin A Receptor antibody IHC of human small intestine, muscularis propria. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TACR2 / NK2R Antibody - Anti-TACR2 / Nk2 / NK2R antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human TACR2 / NK2R Antibody (C‑Terminus, IHC) LS‑A1288

PathPlus™ Polyclonal Rabbit anti‑Human TACR2 / NK2R Antibody (C‑Terminus, IHC) LS‑A1288

Antibody:
TACR2 / NK2R Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$460
LS-A1288-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
TACR2 / NK2R Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
TACR2 (NK2R) is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P. TACR2 functions in GI motility, visceral sensitivity and secretion, and loss of TACR2 has been shown to lead to gastric emptying disturbance. TACR2 is implicated in the mediation of smooth muscle contraction in central airways and the development of asthma. Additionally, TACR2 is believed to play a role in neurological disorders, and antagonists of TACR2 are currently in clinical trials as potential therapies for major depressive disorder. In immunohistochemistry, TACR2 has highest membranous positivity in the gastrointestinal tract, and is also found in the urinary bladder, prostate, reproductive tissues, epithelial cells in the breast, ovary, eccrine glands, stomach and testis, and in smooth muscle in various tissues. References: Neurogastroenterol Motil. 2017 Nov;29(11), PMID: 28585346; CNS Neurol Disord Drug Targets. 2010 Nov;9(5):627-35, PMID: 20632965
Target
Human TACR2 / NK2R
Synonyms
TACR2 | Neurokinin 2 receptor | NK-2 receptor | Neurokinin A receptor | NK2 | NK2R | Tachykinin receptor 2 | Substance-K receptor | NK-2R | SK receptor | SKR | TAC2R | NKNAR | Substance K receptor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 20 amino acid peptide from C-Terminus of human Neurokinin A Receptor. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon (95%); Monkey, Marmoset (85%); Bat, Panda, Guinea pig (80%).
Epitope
C-Terminus
Specificity
Human Neurokinin A Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (15 - 30 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About TACR2 / NK2R
P21452 NM_001057 NP_001048.2

Validation

TACR2 / NK2R Antibody - Breast, Carcinoma
Breast, Carcinoma
Breast, Carcinoma

TACR2 / NK2R Antibody - Ovary, carcinoma
Ovary, carcinoma
Ovary, carcinoma

TACR2 / NK2R Antibody - Skin, Malignant Melanoma
Skin, Malignant Melanoma
Skin, Malignant Melanoma

TACR2 / NK2R Antibody - Anti-TACR2 / Nk2 / NK2R antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TACR2 / Nk2 / NK2R antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TACR2 / Nk2 / NK2R antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TACR2 / NK2R Antibody - Anti-Neurokinin A Receptor antibody IHC of human small intestine, muscularis propria. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Neurokinin A Receptor antibody IHC of human small intestine, muscularis propria. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Neurokinin A Receptor antibody IHC of human small intestine, muscularis propria. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TACR2 / NK2R Antibody - Anti-TACR2 / Nk2 / NK2R antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TACR2 / Nk2 / NK2R antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TACR2 / Nk2 / NK2R antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ TACR2 / NK2R Antibody (C-Terminus) for IHC LS-A1288 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/27/2021