Products
Research Areas
COVID-19
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, Proforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-A962-50 50 µg (1 mg/ml) $460 
PTGER1 / EP1 Antibody - Breast, Carcinoma
PTGER1 / EP1 Antibody - Colon, Carcinoma
PTGER1 / EP1 Antibody - Brain, Glioblastoma
PTGER1 / EP1 Antibody - Lung, Non Small-Cell Carcinoma
PTGER1 / EP1 Antibody - Anti-PTGER1 / EP1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PTGER1 / EP1 Antibody - Anti-PTGER1 / EP1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PTGER1 / EP1 Antibody - Anti-PTGER1 / EP1 antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PTGER1 / EP1 Antibody - Breast, Carcinoma
PTGER1 / EP1 Antibody - Colon, Carcinoma
PTGER1 / EP1 Antibody - Brain, Glioblastoma
PTGER1 / EP1 Antibody - Lung, Non Small-Cell Carcinoma
PTGER1 / EP1 Antibody - Anti-PTGER1 / EP1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PTGER1 / EP1 Antibody - Anti-PTGER1 / EP1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PTGER1 / EP1 Antibody - Anti-PTGER1 / EP1 antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
1 of 7
2 of 7
3 of 7
4 of 7
5 of 7
6 of 7
7 of 7

PathPlus™ Polyclonal Rabbit anti‑Human PTGER1 / EP1 Antibody (Cytoplasmic Domain, IHC) LS‑A962

PathPlus™ Polyclonal Rabbit anti‑Human PTGER1 / EP1 Antibody (Cytoplasmic Domain, IHC) LS‑A962

Antibody:
PTGER1 / EP1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$460
LS-A962-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
PTGER1 / EP1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
PTGER1 (Prostaglandin E receptor EP1) is a member of the Prostanoid Receptor subfamily that mediates the diverse biological effects of prostaglandin E2 (PGE2). PGE2 has been implicated in regulation of the immune response, male erectile function, cervical and colorectal cancer, induction of labor, pain perception, blood pressure, bone resorption, and asthma. It is differentially expressed in the glandular epithelium of the endometrium across different phases of the menstrual cycle, and localizes to either the nucleus or apical membrane depending on the phase. In immunohistochemistry, PTGER1 has membranous positivity in the pituitary and on visceral epithelial cells of the kidney, Leydig cells in the testis, populations of epithelial cells in the lung and kidney, and it is expressed in the glandular epithelium of the endometrium. It is also found in a few other tissues and cell types including the pancreas, skin, stomach, intestinal neuroendocrine cells, the liver, ovarian oocytes and the heart. References: Mol Hum Reprod. 2011 Mar; 17(3): 182–192, PMID: 21112968; J Clin Invest. 2001;107(3):325-331, DOI:10.1172/JCI6749
Target
Human PTGER1 / EP1
Synonyms
PTGER1 | EP1 prostaglandin receptor | PGE receptor EP1 subtype | Prostaglandin E receptor 1 | EP1 | PGE receptor, EP1 subtype | PGE2 receptor EP1 subtype | Prostanoid EP1 receptor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Bovine, Dog, Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human PTGER1 / EP1. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Hamster, Bovine, Dog (94%); Mouse, Rat, Bat (81%).
Epitope
Cytoplasmic Domain
Specificity
Human PTGER1 / EP1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (5 - 10 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About PTGER1 / EP1
P34995 NM_000955 NP_000946.2

Validation

PTGER1 / EP1 Antibody - Breast, Carcinoma
Breast, Carcinoma
Breast, Carcinoma

PTGER1 / EP1 Antibody - Colon, Carcinoma
Colon, Carcinoma
Colon, Carcinoma

PTGER1 / EP1 Antibody - Brain, Glioblastoma
Brain, Glioblastoma
Brain, Glioblastoma

PTGER1 / EP1 Antibody - Lung, Non Small-Cell Carcinoma
Lung, Non Small-Cell Carcinoma
Lung, Non Small-Cell Carcinoma

PTGER1 / EP1 Antibody - Anti-PTGER1 / EP1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTGER1 / EP1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTGER1 / EP1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PTGER1 / EP1 Antibody - Anti-PTGER1 / EP1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTGER1 / EP1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTGER1 / EP1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PTGER1 / EP1 Antibody - Anti-PTGER1 / EP1 antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTGER1 / EP1 antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTGER1 / EP1 antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ PTGER1 / EP1 Antibody (Cytoplasmic Domain) for IHC LS-A962 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)

Publications (1)

Antagonism of the prostaglandin E2 EP1 receptor in MDCK cells increases growth through activation of Akt and the epidermal growth factor receptor. Taub M, Parker R, Mathivanan P, Ariff MA, Rudra T. American journal of physiology. Renal physiology. 2015 Sep;307:F539-50.

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/16/2021