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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-B8704-100 100 µg (1 mg/ml) $425 
LYZ / Lysozyme Antibody - Anti-LYZ / Lysozyme antibody IHC staining of human small intestine, crypt. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PathPlus™ Monoclonal Mouse anti‑Human LYZ / Lysozyme Antibody (clone SB1 (BGN/06/961), IHC, WB) LS‑B8704

PathPlus™ Monoclonal Mouse anti‑Human LYZ / Lysozyme Antibody (clone SB1 (BGN/06/961), IHC, WB) LS‑B8704

Note: This antibody replaces LS-C42024
Antibody:
LYZ / Lysozyme Mouse anti-Human Monoclonal (SB1 (BGN/06/961)) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$425
LS-B8704-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
LYZ / Lysozyme Mouse anti-Human Monoclonal (SB1 (BGN/06/961)) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Lysozyme (Muramidase, LYZ) is a bacteriolytic and histiocytic enzyme that functions in the immune system as a defense mechanism against certain pathogens. Lysozyme can break down the peptidoglycans that compose gram-positive bacterial cell walls (such as Streptococcus and Bacillus). High levels of lysozyme are present in egg white, and in humans it is found in secreted mucus, tears, saliva, and milk. It is also expressed in macrophages and polymorphonuclear neutrophils. In immunohistochemistry, lysozyme stains positively in histiocytes, monocytes, neutrophils, macrophages, goblet cells, lactating lobules of the breast, some epithelial cells and normal hematopoietic cells. In cancer, it is positive in myeloid leukemias where it can by highly overexpressed, acinic cell carcinomas of the breast and salivary gland, goblet cell carcinoids, myeloid sarcomas and various histiocytic lesions. References: Am J Surg Pathol. 2009. 33:1137, PMID: 19461506; CRC Press. 1994. p. 223. ISBN: 978-0-8493-8935-1; McGraw-Hill Higher Education. 2007. ISBN: 978-0-07-110706-8; Am J Clin Pathol. 1992 Feb;97(2):195-201, PMID: 1546687
Target
Human LYZ / Lysozyme
Synonyms
LYZ | 1,4-beta-N-acetylmuramidase C | LZM | Lysozyme | Lysozyme (renal amyloidosis) | Renal amyloidosis | Lysozyme C | Gal d 4 | P00698
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
SB1 (BGN/06/961)
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Human lysozyme purified from urine.
Specificity
Recognizes lysozyme, an enzyme that is present in mucosal secretions such as saliva and tears that is involved with non-specific organism defense. It functions by hydrolyzing 1,2-beta linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues such as those found in the walls of various Gram-positive bacteria.
Applications
  • IHC
  • IHC - Paraffin (20 µg/ml)
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About LYZ / Lysozyme
P61626 NM_000239 NP_000230.1

Validation

LYZ / Lysozyme Antibody - Anti-LYZ / Lysozyme antibody IHC staining of human small intestine, crypt. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-LYZ / Lysozyme antibody IHC staining of human small intestine, crypt. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-LYZ / Lysozyme antibody IHC staining of human small intestine, crypt. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ LYZ / Lysozyme Antibody (clone SB1 (BGN/06/961)) for IHC, WB/Western, ELISA LS-B8704 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/25/2020