Products
Research Areas
COVID-19
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, Proforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-B16251-100 100 µg (200 µg/ml) $485 
KRT16 / CK16 / Cytokeratin 16 Antibody - Human Hair Follicle: Formalin-Fixed, Paraffin-Embedded (FFPE)
KRT16 / CK16 / Cytokeratin 16 Antibody - SDS-PAGE Analysis Purified CK16 Mouse Recombinant Monoclonal Antibody (rKRT16/1714). Confirmation of Purity and Integrity of Antibody.
KRT16 / CK16 / Cytokeratin 16 Antibody - Human Hair Follicle: Formalin-Fixed, Paraffin-Embedded (FFPE)
KRT16 / CK16 / Cytokeratin 16 Antibody - SDS-PAGE Analysis Purified CK16 Mouse Recombinant Monoclonal Antibody (rKRT16/1714). Confirmation of Purity and Integrity of Antibody.
1 of 2
2 of 2

PathPlus™ Recombinant Monoclonal Mouse anti‑Human KRT16 / CK16 / Cytokeratin 16 Antibody (clone rKRT16/1714, C‑Terminus, IHC) LS‑B16251

PathPlus™ Recombinant Monoclonal Mouse anti‑Human KRT16 / CK16 / Cytokeratin 16 Antibody (clone rKRT16/1714, C‑Terminus, IHC) LS‑B16251

Note: This antibody replaces LS-C751234
Antibody:
KRT16 / CK16 / Cytokeratin 16 Mouse anti-Human Recombinant Monoclonal (C-Terminus) (rKRT16/1714) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$485
LS-B16251-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
KRT16 / CK16 / Cytokeratin 16 Mouse anti-Human Recombinant Monoclonal (C-Terminus) (rKRT16/1714) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
KRT16 (Cytokeratin 16, CK16) is a type I cytokeratin that partners with Keratin 6A to form keratin intermediate filaments. KRT16 is found in non-keratinizing squamous epithelium of the esophagus, tongue, oral cavity, tonsil, ectocervix, vagina, and in melanocytes, hair follicles and nails. Increased expression is found in conditions involving hyperplastic keratinocytes, including psoriasis, and decreased expression is observed in cervical carcinoma. Mutations are associated with pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus syndromes. References: J Anat 2009 214(4):516; Am J Dermatopath 2005 27(6):476; Exp Dermatol 2013 22(12):838; Human Mol Genet 2019:doi.org/10.1093/ddz050
Target
Human KRT16 / CK16 / Cytokeratin 16
Synonyms
KRT16 | CK16 | Cytokeratin 16 | Cytokeratin-16 | FNEPPK | K1CP | Keratin-16 | Keratin 16 | NEPPK | CK-16 | K16 | KRT16A
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Recombinant Monoclonal
Clone
rKRT16/1714
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Unmodified. Also available Azide-free, Carrier-free.
Immunogen
Recombinant fragment from the C-Terminus of human Cytokeratin 16. Antigen Molecular Weight: 48 kDa
Epitope
C-Terminus
Specificity
Cytokeratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.
Applications
  • IHC - Paraffin (1:50)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Immunohistology (Frozen & Formalin-fixed - 0.5-1 ug/ml for 30 min at RT - Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.
Presentation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Storage
Store at 2°C to 8°C for up to 2 years.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About KRT16 / CK16 / Cytokeratin 16
P08779 NM_005557 NP_005548.2

Validation

KRT16 / CK16 / Cytokeratin 16 Antibody - Human Hair Follicle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Hair Follicle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Hair Follicle: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ KRT16 / CK16 / Cytokeratin 16 Antibody (C-Terminus, clone rKRT16/1714) for IHC LS-B16251 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/24/2021