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Catalog Number Size Price
LS-B15876-50 50 µl (1 mg/ml) $460 
KCNJ2 / Kir2.1 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
KCNJ2 / Kir2.1 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
KCNJ2 / Kir2.1 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
KCNJ2 / Kir2.1 Antibody - Western blot analysis of Kir2.1 expression in HeLa (A); mouse brain (B); rat kidney (C) whole cell lysates.
KCNJ2 / Kir2.1 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
KCNJ2 / Kir2.1 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
KCNJ2 / Kir2.1 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
KCNJ2 / Kir2.1 Antibody - Western blot analysis of Kir2.1 expression in HeLa (A); mouse brain (B); rat kidney (C) whole cell lysates.
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PathPlus™ Polyclonal Rabbit anti‑Human KCNJ2 / Kir2.1 Antibody (Internal, IHC, WB) LS‑B15876

PathPlus™ Polyclonal Rabbit anti‑Human KCNJ2 / Kir2.1 Antibody (Internal, IHC, WB) LS‑B15876

Note: This antibody replaces LS-C358787
Antibody:
KCNJ2 / Kir2.1 Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B15876-50
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
KCNJ2 / Kir2.1 Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
KCNJ2 (Kir2.1 inward-rectifier potassium ion channel) is a potassium ion channel protein that maintains resting membrane potential and regulates cell excitability. It plays an important role in neural and craniofacial development. It is highly expressed in the hippocampus, nucleus accumbens, putamen and caudate in the brain as well as in skeletal muscle, and is central to the inward-rectifier current (IK1) that controls cardiac excitability in human ventricular muscle. Mutations in KCNJ2 affect neuronal excitability and are associated with Autism, short-QT syndrome and Andersen-Tawil syndrome. In immunohistochemistry, KCNJ2 has cytoplasmic positivity in most tissues throughout the body. References: Front. Cell. Neurosci. 2018, DOI: 10.3389/fncel.2018.00076; Heart Rhythm. 2005 Mar;2(3):316-24, PMID: 15851327; Cardiovascular Research. 2012. 93 (4): 666–673, DOI:10.1093/cvr/cvr329; J Physiol. 2016 Jun 15;594(12):3245-70, PMID: 26864374
Target
Human KCNJ2 / Kir2.1
Synonyms
KCNJ2 | ATFB9 | HHBIRK1 | IRK1 | KIR2.1 | LQT7 | HIRK1 | IRK-1 | HHIRK1 | SQT3
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the central region of human Kir2.1.
Epitope
Internal
Specificity
Recognizes endogenous levels of Kir2.1 protein.
Applications
  • IHC - Paraffin (5 µg/ml)
  • Western blot (1:500 - 1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol
Storage
Aliquot and store at -20°C for 1 year. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About KCNJ2 / Kir2.1
P63252 NM_000891 NP_000882.1

Validation

KCNJ2 / Kir2.1 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

KCNJ2 / Kir2.1 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

KCNJ2 / Kir2.1 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ KCNJ2 / Kir2.1 Antibody (Internal) for IHC, WB/Western LS-B15876 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 5/17/2021