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Catalog Number Size Price
LS-B1358-50 50 µg (1 mg/ml) $545 
HTRA2 / OMI Antibody - Anti-HTRA2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
HTRA2 / OMI Antibody - Anti-HTRA2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
HTRA2 / OMI Antibody - Immunofluorescence of OMI in Human Liver cells with OMI antibody at 20 ug/ml.
HTRA2 / OMI Antibody - Western blot of OMI in U937 lysate with Omi antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.
HTRA2 / OMI Antibody - Anti-HTRA2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
HTRA2 / OMI Antibody - Anti-HTRA2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
HTRA2 / OMI Antibody - Immunofluorescence of OMI in Human Liver cells with OMI antibody at 20 ug/ml.
HTRA2 / OMI Antibody - Western blot of OMI in U937 lysate with Omi antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.
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PathPlus™ Polyclonal Rabbit anti‑Human HTRA2 / OMI Antibody (IHC, IF, WB) LS‑B1358

PathPlus™ Polyclonal Rabbit anti‑Human HTRA2 / OMI Antibody (IHC, IF, WB) LS‑B1358

Note: This antibody replaces LS-C19471, LS-C56776, LS-C42336
Antibody:
HTRA2 / OMI Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, IF, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$545
LS-B1358-50
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
HTRA2 / OMI Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, IF, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
HTRA2 (Omi, Prss25, mnd2) is a mitochondrial serine protease protease that regulates mitochondrial homeostasis and molecular quality control and is involved in caspase-dependent apoptosis. HTRA2 dysfunction or mutation is implicated in the pathogenesis of neurodegenerative syndromes such as Parkinson’s disease and neuromuscular disorders and juvenile lethality in mice. HTRA2 is also differentially expressed expressed in various cancers relative to normal tissue and is thought to be involved in tumorigenesis. In immunohistochemistry of normal tissue, HTRA2 has cytoplasmic positivity in a majority of tissues throughout the body. References: Int J Cell Biol. 2012;2012:607929, PMID: 22675361; Nature. 2003 Oct 16;425(6959):721-7, PMID: 14534547; APMIS. 111 (5): 586–90, PMID: 12887511;
Target
Human HTRA2 / OMI
Synonyms
HTRA2 | HtrA-like serine protease | OMI | PARK13 | Protease, serine, 25 | PRSS25 | Serine protease 25 | HtrA serine peptidase 2 | Serine proteinase OMI
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Ion exchange chromatography
Modifications
Unmodified
Immunogen
A peptide corresponding to 16 AA near the C-Terminus of human Omi. The immunogen is located within aa 70-120 of OMI.
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Immunofluorescence
  • Western blot (0.5 - 1 µg/ml)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
OMI antibody can be used for detection of OMI by Western blot at 0.5 to 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2 ug/mL. For immunofluorescence start at 20 ug/mL. Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Western Blot:
Presentation
PBS containing 0.02% Sodium Azide
Storage
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About HTRA2 / OMI
O43464 NM_013247 NP_037379.1

Validation

HTRA2 / OMI Antibody - Anti-HTRA2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-HTRA2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-HTRA2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

HTRA2 / OMI Antibody - Anti-HTRA2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-HTRA2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-HTRA2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

LSBio Ratings

PathPlus™ HTRA2 / OMI Antibody for IHC, IF/Immunofluorescence, WB/Western, ELISA LS-B1358 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/16/2021