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Catalog Number Size Price
LS-A4998-50 50 µg (1 mg/ml) $460 
GRM6 / MGLUR6 Antibody - Anti-GRM6 / MGLUR6 antibody IHC of human eye, ganglion cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM6 / MGLUR6 Antibody - Brain, glioblastoma
GRM6 / MGLUR6 Antibody - Eye, Retina
GRM6 / MGLUR6 Antibody - Anti-GRM6 / MGLUR6 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM6 / MGLUR6 Antibody - Anti-GRM6 / MGLUR6 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM6 / MGLUR6 Antibody - Anti-GRM6 / MGLUR6 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM6 / MGLUR6 Antibody - Anti-GRM6 / MGLUR6 antibody IHC of human eye, ganglion cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM6 / MGLUR6 Antibody - Brain, glioblastoma
GRM6 / MGLUR6 Antibody - Eye, Retina
GRM6 / MGLUR6 Antibody - Anti-GRM6 / MGLUR6 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM6 / MGLUR6 Antibody - Anti-GRM6 / MGLUR6 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM6 / MGLUR6 Antibody - Anti-GRM6 / MGLUR6 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human GRM6 / MGLUR6 Antibody (N‑Terminus, IHC) LS‑A4998

PathPlus™ Polyclonal Rabbit anti‑Human GRM6 / MGLUR6 Antibody (N‑Terminus, IHC) LS‑A4998

Antibody:
GRM6 / MGLUR6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-A4998-50

Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
GRM6 / MGLUR6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified

Specifications

Description
Glutamate receptor, metabotropic 6 (GRM6) binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties.Group III receptors are linked to the inhibition of the cyclic AMP signaling cascade, but differ in their agonist selectivities. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human GRM6 / MGLUR6
Synonyms
GRM6 | CSNB1B | GPRC1F | MGlu6 | MGLUR6
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 12 amino acid peptide from N-Terminus extracellular domain of human GRM6 / MGLUR6. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Marmoset (100%); Rat, Dog, Panda, Rabbit (83%).
Epitope
N-Terminus
Specificity
Human GRM6 / MGLUR6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (5.6 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Immunohistochemistry: The unconjugated form was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for the unconjugated form was determined to be 5.6 ug/ml.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GRM6 / MGLUR6
O15303 NM_000843 AAB82068.1

Validation

GRM6 / MGLUR6 Antibody - Anti-GRM6 / MGLUR6 antibody IHC of human eye, ganglion cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM6 / MGLUR6 antibody IHC of human eye, ganglion cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM6 / MGLUR6 antibody IHC of human eye, ganglion cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GRM6 / MGLUR6 Antibody - Brain, glioblastoma
Brain, glioblastoma
Brain, glioblastoma

GRM6 / MGLUR6 Antibody - Eye, Retina
Eye, Retina
Eye, Retina

GRM6 / MGLUR6 Antibody - Anti-GRM6 / MGLUR6 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM6 / MGLUR6 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM6 / MGLUR6 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GRM6 / MGLUR6 Antibody - Anti-GRM6 / MGLUR6 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM6 / MGLUR6 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM6 / MGLUR6 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GRM6 / MGLUR6 Antibody - Anti-GRM6 / MGLUR6 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM6 / MGLUR6 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM6 / MGLUR6 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ GRM6 / MGLUR6 Antibody (N-Terminus) for IHC LS-A4998 has an LSBio Rating of
Laboratory Validation Score (5)

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Requested From: United States
Date Requested: 5/23/2024