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Catalog Number Size Price
LS-B5423-50 50 µg $440 
FOXA2 Antibody - Anti-FOXA2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
FOXA2 Antibody - FOXA2 monoclonal antibody clone 2F12 Western blot of FOXA2 expression in HepG2.
FOXA2 Antibody - Detection limit for recombinant GST tagged FOXA2 is approximately 0.1 ng/ml as a capture antibody.
FOXA2 Antibody - Anti-FOXA2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
FOXA2 Antibody - FOXA2 monoclonal antibody clone 2F12 Western blot of FOXA2 expression in HepG2.
FOXA2 Antibody - Detection limit for recombinant GST tagged FOXA2 is approximately 0.1 ng/ml as a capture antibody.
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PathPlus™ Monoclonal Mouse anti‑Human FOXA2 Antibody (clone 2F12, IHC, WB) LS‑B5423

PathPlus™ Monoclonal Mouse anti‑Human FOXA2 Antibody (clone 2F12, IHC, WB) LS‑B5423

Note: This antibody replaces LS-C133251
Antibody:
FOXA2 Mouse anti-Human Monoclonal (2F12) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-B5423-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
FOXA2 Mouse anti-Human Monoclonal (2F12) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
FOXA2 (forkhead box protein A2, HNF-3B, TCF-3B) is a transcription factor that activates albumin, transthyretin and other liver-specific genes. It is involved in the differentiation of cells in the pancreas and liver, lipid metabolic regulation and ketogenesis. FOXA2 also plays an important role in the maintenance of dopamine neurons in adults, and it is required for the proper differentiation of mesodiencephalic dopaminergic neurons during development. Downregulation of FOXA2 is implicated in lipid accumulation and insulin resistance in the liver in fasting and diabetes. Lowered levels of FOXA2 are also correlated with invasive properties in hepatocellular carcinoma. In immunohistochemistry of normal adult tissue, FOXA2 primarily has nuclear positivity in the pancreas, liver, lung, gastrointestinal tract, urinary bladder, prostate, endometrium, fallopian tube and appendix. References: Nature. 2004 Dec 23;432(7020):1027-32, PMID: 15616563; Carcinogenesis. 2014. 35(11): 2576–2583, DOI: 10.1093/carcin/bgu180; Journal of Neuroscience. 2013. 33 (18): 8022-8034, DOI: 10.1523/JNEUROSCI.4774-12.2013; Front Cell Neurosci. 2014; 8: 275, PMID: 25249938;
Target
Human FOXA2
Synonyms
FOXA2 | HNF3B | HNF-3-beta | HNF-3B | TCF3B | Transcription factor 3B | Forkhead box A2 | Forkhead box protein A2 | Hepatic nuclear factor-3-beta | TCF-3B
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a,k Monoclonal
Clone
2F12
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Immunogen
FOXA2 (NP_068556, 363 aa ~ 458 aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human FOXA2
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot: Cell lysate, Recombinant protein.
Presentation
PBS, pH 7.4
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About FOXA2
Q9Y261 NM_021784 NP_068556.2

Validation

FOXA2 Antibody - Anti-FOXA2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-FOXA2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-FOXA2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

LSBio Ratings

PathPlus™ FOXA2 Antibody (clone 2F12) for IHC, WB/Western, ELISA LS-B5423 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 6/15/2024