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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16429-50 | 50 µg | $460 |
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PathPlus™ Monoclonal Mouse anti‑Human Cytokeratin 4+5+6+8+10+13+18 Antibody (clone C11, IHC, WB) LS‑B16429
PathPlus™ Monoclonal Mouse anti‑Human Cytokeratin 4+5+6+8+10+13+18 Antibody (clone C11, IHC, WB) LS‑B16429
Note: This antibody replaces LS-C140502
Antibody:
Cytokeratin 4+5+6+8+10+13+18 Mouse anti-Human Monoclonal (C11) Antibody
Application:
IHC-P, IHC-Fr, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
Cytokeratin 4+5+6+8+10+13+18 Mouse anti-Human Monoclonal (C11) Antibody
Application:
IHC-P, IHC-Fr, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Antibodies to the pan-keratin group Cytokeratin 4+5+6+8+10+13+18, such as monoclonal antibody C-11, are broad spectrum antibodies used to differentiate epithelial tumors from non-epithelial tumors. C11 has been shown to be useful alongside additional keratin cocktails for identifying circulating tumor cells in breast and other cancers.
References; Clin Cancer Res. 2012 Feb 15;18(4):993-1003, PMID: 22228641; Sci Rep. 2015; 5: 12270, PMID: 26184843; Br J Cancer 102, 1533–1540 (2010) doi:10.1038/sj.bjc.6605652
Target
Human Cytokeratin 4+5+6+8+10+13+18
Synonyms
Cytokeratin 4 5 6 8 10 13 18 | KRT4/5/6/8/10/13/18 | Multi Cytokeratin Antibody | Pan Cytokeratin
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
C11
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Unmodified
Immunogen
Cytoskeleton preparation from human A431 carcinoma cells and mouse myeloma cells.
Specificity
Human Keratin 4/5/6/8/10/13/18
Applications
- IHC - Paraffin (10 µg/ml)
- IHC - Frozen
- Western blot
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Detect keratins 4,5,6,8,10,13 & 18 by Western blot. Optimal concentration should be evaluated by serial dilutions. Other Applications: Frozen Tissue Staining, Paraffin Section, Immunohistochemistry.
Presentation
PBS, 0.08% Sodium Azide
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Validation
Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ Cytokeratin 4+5+6+8+10+13+18 Antibody (clone C11) for IHC, WB/Western LS-B16429 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse, Rat, Bovine
Applications:
IHC - Paraffin, ICC
Reactivity:
Mouse
Range:
0.156-10 ng/ml
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit, Chicken, Xenopus
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/28/2024
Date Requested: 4/28/2024
