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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16088-100 | 100 µl (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human CNN1 / Calponin Antibody (Internal, IHC, WB) LS‑B16088
PathPlus™ Polyclonal Rabbit anti‑Human CNN1 / Calponin Antibody (Internal, IHC, WB) LS‑B16088
Note: This antibody replaces LS-C354304
Antibody:
CNN1 / Calponin Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
CNN1 / Calponin Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
Calponin (CNN1) is a smooth muscle protein with functional roles in proliferation, angiogenesis and migration (O’Kelly, 2008). It is a negative regulator of smooth muscle contraction via its inhibition of actomyosin interaction. As a marker, calponin is used to identify myoepithelial cells. It stains positively in the cytoplasm around the nucleus in myoepithelial cells, stromal myofibroblasts, and vascular smooth muscle.
References: Intl J Onc. 2008 Jul; 33.1; 59-67, PMID: 18575751; Clin Onc. 2014 Aug; 5.3; 382-392, PMID: 25114853; Trends Biochem Sci. 1994 Sep;19(9):362-8, PMID: 7985229
Target
Human CNN1 / Calponin
Synonyms
CNN1 | Basic calponin | Calponin | Calponin-1 | Calponins, basic | Calponin H1, smooth muscle | SMCC | Sm-Calp
Host
Rabbit
Reactivity
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the central region of human Calponin 1.
Epitope
Internal
Specificity
Recognizes endogenous levels of Calponin 1 protein.
Applications
- IHC - Paraffin (1:100)
- Western blot (1:500 - 1:1000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CNN1 / Calponin
Validation
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ CNN1 / Calponin Antibody (Internal) for IHC, WB/Western LS-B16088 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Reactivity:
Mouse
Range:
0.313-20 ng/ml
Reactivity:
Human
Range:
0.312-20 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/28/2024
Date Requested: 4/28/2024
