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Catalog Number Size Price
LS-A1333-50 50 µg (1 mg/ml) $440 
CHRM2 / M2 Antibody - Brain, HypothalamusBrain, glioblastoma
CHRM2 / M2 Antibody - Brain, Amygdala neuron
CHRM2 / M2 Antibody - Brain, Hypothalamus
CHRM2 / M2 Antibody - Anti-CHRM2 / M2 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CHRM2 / M2 Antibody - Anti-CHRM2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CHRM2 / M2 Antibody - Anti-CHRM2 / M2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CHRM2 / M2 Antibody - Anti-CHRM2 / M2 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CHRM2 / M2 Antibody - Brain, HypothalamusBrain, glioblastoma
CHRM2 / M2 Antibody - Brain, Amygdala neuron
CHRM2 / M2 Antibody - Brain, Hypothalamus
CHRM2 / M2 Antibody - Anti-CHRM2 / M2 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CHRM2 / M2 Antibody - Anti-CHRM2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CHRM2 / M2 Antibody - Anti-CHRM2 / M2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
CHRM2 / M2 Antibody - Anti-CHRM2 / M2 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human CHRM2 / M2 Antibody (Cytoplasmic Domain, IHC) LS‑A1333

PathPlus™ Polyclonal Rabbit anti‑Human CHRM2 / M2 Antibody (Cytoplasmic Domain, IHC) LS‑A1333

Antibody:
CHRM2 / M2 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$440
LS-A1333-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
CHRM2 / M2 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Cholinergic receptor, muscarinic 2 (CHRM2) is a receptor for acetylcholine and is involved in adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. CHRM2 influences many effects of acetylcholine in the central and peripheral nervous system. CHRM2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human CHRM2 / M2
Synonyms
CHRM2 | 7TM receptor | HM2 | M2 muscarinic receptor | M2-mAChR | Muscarinic receptor M2 | Muscarinic M2 receptor
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep (tested or 100% immunogen sequence identity)
Predicted
Bat, Chicken (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human CHRM2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Sheep, Dog, Bovine, Hamster, Elephant, Panda, Horse, Rabbit, Pig, Guinea pig (100%); Bat, Opossum, Turkey, Chicken (94%); Xenopus (88%); Platypus, Zebrafish, Stickleback (81%).
Epitope
Cytoplasmic Domain
Specificity
Human CHRM2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (6 - 15 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CHRM2 / M2
P08172 NM_000739 NP_000730.1

Validation

CHRM2 / M2 Antibody - Brain, HypothalamusBrain, glioblastoma
Brain, HypothalamusBrain, glioblastoma
Brain, HypothalamusBrain, glioblastoma

CHRM2 / M2 Antibody - Brain, Amygdala neuron
Brain, Amygdala neuron
Brain, Amygdala neuron

CHRM2 / M2 Antibody - Brain, Hypothalamus
Brain, Hypothalamus
Brain, Hypothalamus

CHRM2 / M2 Antibody - Anti-CHRM2 / M2 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CHRM2 / M2 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CHRM2 / M2 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

CHRM2 / M2 Antibody - Anti-CHRM2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CHRM2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CHRM2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

CHRM2 / M2 Antibody - Anti-CHRM2 / M2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CHRM2 / M2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CHRM2 / M2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

CHRM2 / M2 Antibody - Anti-CHRM2 / M2 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CHRM2 / M2 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CHRM2 / M2 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ CHRM2 / M2 Antibody (Cytoplasmic Domain) for IHC LS-A1333 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/28/2021