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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-B16238-100 100 µg (200 µg/ml) $485 
CDH16 / Cadherin 16 Antibody - Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
CDH16 / Cadherin 16 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
CDH16 / Cadherin 16 Antibody - Western blot analysis of human kidney tissue lysate using KSP-Cadherin Recombinant Mouse Monoclonal Antibody (rCDH16/1071).
CDH16 / Cadherin 16 Antibody - SDS-PAGE Analysis Purified KSP-Cadherin Recombinant Mouse Monoclonal Antibody (rCDH16/1071). Confirmation of Purity and Integrity of Antibody.
CDH16 / Cadherin 16 Antibody - Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
CDH16 / Cadherin 16 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
CDH16 / Cadherin 16 Antibody - Western blot analysis of human kidney tissue lysate using KSP-Cadherin Recombinant Mouse Monoclonal Antibody (rCDH16/1071).
CDH16 / Cadherin 16 Antibody - SDS-PAGE Analysis Purified KSP-Cadherin Recombinant Mouse Monoclonal Antibody (rCDH16/1071). Confirmation of Purity and Integrity of Antibody.
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PathPlus™ Recombinant Monoclonal Mouse anti‑Human CDH16 / Cadherin 16 Antibody (clone rCDH16/1071, IHC, WB) LS‑B16238

PathPlus™ Recombinant Monoclonal Mouse anti‑Human CDH16 / Cadherin 16 Antibody (clone rCDH16/1071, IHC, WB) LS‑B16238

Note: This antibody replaces LS-C751076
Antibody:
CDH16 / Cadherin 16 Mouse anti-Human Recombinant Monoclonal (rCDH16/1071) Antibody
Application:
IHC-P, WB, Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$485
LS-B16238-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
CDH16 / Cadherin 16 Mouse anti-Human Recombinant Monoclonal (rCDH16/1071) Antibody
Application:
IHC-P, WB, Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
CDH16 (Cadherin 16) is a calcium dependent membrane glycoprotein found in the tubular epithelium of the adult kidney and thyroid gland, where it functions as the principal mediator of homotypic cell recognition. Is plays a role in renal tissue development during embryogenesis. References: Endocrinology 2012, 153 1:522; JASN 2002 13(7):1837; Am J Surg Path 2007 31(10):1528
Target
Human CDH16 / Cadherin 16
Synonyms
CDH16 | Cadherin 16, KSP-cadherin | Cadherin 16 | Cadherin-16 | Kidney-specific cadherin | KSP-cadherin
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Recombinant Monoclonal
Clone
rCDH16/1071
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Unmodified. Also available Azide-free, Carrier-free.
Immunogen
Recombinant full-length human CDH16 protein. Antigen Molecular Weight: 130 kDa
Specificity
This MAb recognizes a protein of 130 kDa , identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Applications
  • IHC - Paraffin (1:50)
  • Western blot (1 - 2 µg/ml)
  • Flow Cytometry (1 - 2 µg/10E6 cells)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Western Blotting (1-2 ug/ml) - Immunohistology (Formalin-fixed - 1-2 ug/ml for 30 minutes at RT - Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.
Presentation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Storage
Store at 2°C to 8°C for up to 2 years.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CDH16 / Cadherin 16
O75309 NM_004062 NP_004053.1

Validation

CDH16 / Cadherin 16 Antibody - Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)

CDH16 / Cadherin 16 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ CDH16 / Cadherin 16 Antibody (clone rCDH16/1071) for IHC, WB/Western, Flow LS-B16238 has an LSBio Rating of
Laboratory Validation Score (5)

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 2/24/2021