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Catalog Number Size Price
LS-B7293-0.1 0.1 mg (1 mg/ml) $460 
CD45RB Antibody - Human Tonsil, Lymphocytes: Formalin-Fixed, Paraffin-Embedded (FFPE)
CD45RB Antibody - Anti-CD45RB antibody IHC of human spleen, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CD45RB Antibody - Human Tonsil, Lymphocytes: Formalin-Fixed, Paraffin-Embedded (FFPE)
CD45RB Antibody - Anti-CD45RB antibody IHC of human spleen, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PathPlus™ Monoclonal Mouse anti‑Human CD45RB Antibody (clone MEM‑55, IHC) LS‑B7293

PathPlus™ Monoclonal Mouse anti‑Human CD45RB Antibody (clone MEM‑55, IHC) LS‑B7293

Note: This antibody replaces LS-C11530, LS-C57195
Antibody:
CD45RB Mouse anti-Human Monoclonal (MEM-55) Antibody
Application:
IHC, IHC-P, IHC-Fr, IP, Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$460
LS-B7293-0.1
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
CD45RB Mouse anti-Human Monoclonal (MEM-55) Antibody
Application:
IHC, IHC-P, IHC-Fr, IP, Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
CD45RB is a splice isoform of CD45 (also called protein tyrosine phosphatase, receptor type, C), a glycoprotein receptor that is required for T-cell activation. Several different splice isoforms of the extracellular domain of CD45 are expressed on T cells, and the isoform expressed depends on the particular subpopulation of cell, the state of cell maturation, and whether the cells have been exposed to antigen. CD45RB is expressed in bone marrow and immune system tissues, on naive T cells, peripheral B cells, thymocytes, dendritic cells, and macrophages. CD45RB expression decreases as T cells progress from naive T cells to memory cells. It is positive in most leukemias and lymphomas, but negative in Langerhans cells and plasma cell tumors. References: J Exp Med. 1987;166(5):1548-1566. doi: 10.1084/jem.166.5.1548;Proc Natl Acad Sci U S A. 1988;85(19):7182-7186. doi: 10.1073/pnas.85.19.7182;Trends Immunol. 2006;27(3):146-153. doi: 10.1016/j.it.2006.01.001;Immunol Cell Biol. 1997;75(5):430-445. doi: 10.1038/icb.1997.68;Eur J Immunol 1995 25(2):317.
Target
Human CD45RB
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Non-Reactivity
Goat, Llama
Clonality
IgG1 Monoclonal
Clone
MEM-55
Conjugations
Unconjugated. Also available conjugated with FITC, APC.
Purification
Protein A purified
Modifications
Unmodified
Immunogen
Human lymphocytes.
Specificity
Recognizes the isoform of the leucocyte common antigen encoded by exon B and stains B cells, most T cells and monocytes. Immunoprecipitates bands of 190, 200 and 205 kD.
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry (1:50 - 1:100)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul.
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

Validation

CD45RB Antibody - Human Tonsil, Lymphocytes: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil, Lymphocytes: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil, Lymphocytes: Formalin-Fixed, Paraffin-Embedded (FFPE)

CD45RB Antibody - Anti-CD45RB antibody IHC of human spleen, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-CD45RB antibody IHC of human spleen, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-CD45RB antibody IHC of human spleen, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

LSBio Ratings

PathPlus™ CD45RB Antibody (clone MEM-55) for IHC, IP, Flow LS-B7293 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 5/21/2024