Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (800) 227-6666


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-B16860-50 50 µl (1 mg/ml) $460 
CALB1 / Calbindin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
CALB1 / Calbindin Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
CALB1 / Calbindin Antibody - Western Blot; Sample: Lane1: Mouse Brain Tissue; Lane2: Mouse Kidney Tissue; Lane3: Mouse Eye Tissue.
CALB1 / Calbindin Antibody - Western Blot; Sample: Recombinant CALB, Mouse.
CALB1 / Calbindin Antibody - Western blot of recombinant CALB1 / Calbindin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CALB1 / Calbindin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
CALB1 / Calbindin Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
CALB1 / Calbindin Antibody - Western Blot; Sample: Lane1: Mouse Brain Tissue; Lane2: Mouse Kidney Tissue; Lane3: Mouse Eye Tissue.
CALB1 / Calbindin Antibody - Western Blot; Sample: Recombinant CALB, Mouse.
CALB1 / Calbindin Antibody - Western blot of recombinant CALB1 / Calbindin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
1 of 5
2 of 5
3 of 5
4 of 5
5 of 5

PathPlus™ Polyclonal Rabbit anti‑Mouse CALB1 / Calbindin Antibody (aa3‑261, IHC, WB) LS‑B16860

PathPlus™ Polyclonal Rabbit anti‑Mouse CALB1 / Calbindin Antibody (aa3‑261, IHC, WB) LS‑B16860

Note: This antibody replaces LS-C293103
Antibody:
CALB1 / Calbindin Rabbit anti-Mouse Polyclonal (aa3-261) Antibody
Application:
IHC-P, WB
Reactivity:
Mouse, Rat
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$460
LS-B16860-50
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
CALB1 / Calbindin Rabbit anti-Mouse Polyclonal (aa3-261) Antibody
Application:
IHC-P, WB
Reactivity:
Mouse, Rat
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
CALB1 (Calbindin) is a protein of the calcium-binding protein superfamily. It functions to buffer the entry of calcium upon glutamate receptor stimulation. In the brain, it is involved in synaptic plasticity. CALB1 has high levels of expression in neurons, and it is associated with sex-specific behavioral regulation and neurobehavioral diseases. Loss of CALB1 in mice results in reduced levels of anxiety, and in humans loss of this protein has been found in patients with Huntington disease. Furthermore, downregulation of CALB1 is seen in Alzheimer’s disease (AD) and it is associated with cognitive and memory deficits in AD as well as seizure-prone neurological disorders. In immunohistochemistry, CALB1 has cytoplasmic positivity in Purkinje cells in the cerebellum, in neurons in the cerebral cortex and hippocampus, and in renal tubules. References: Endocrinology. 2016 May; 157(5): 1967–1979, PMID: 27010449; Nat Med. 2017 Nov;23(11):1377-1383, PMID: 29035369; Cell Rep. 2017 Oct 24;21(4):891-900, PMID: 29069596; Int J Neurosci. 2005 Oct;115(10):1375-82, PMID: 16162445;
Target
Mouse CALB1 / Calbindin
Synonyms
CALB1 | Calbindin D28 | Calbindin | Calbindin 1, 28kDa | CAB27 | CALB | RTVL-H protein | Calbindin 1, (28kD) | D-28K
Host
Rabbit
Reactivity
Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, Cy3, HRP, APC, PE, APC, Cy7.
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Modifications
Unmodified
Immunogen
Recombinant CALB (Glu3-Asn261) expressed in E. coli.
Epitope
aa3-261
Specificity
The antibody is a rabbit polyclonal antibody raised against CALB.
Applications
  • IHC - Paraffin (10 µg/ml)
  • Western blot (1:100 - 1:400)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
ICC 5-20ug/ml; WB 0.5-2ug/ml;
Presentation
PBS, pH 7.4, 0.02% Sodium Azide, 50% Glycerol
Storage
Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CALB1 / Calbindin
P05937 NM_004929 NP_004920.1

Validation

CALB1 / Calbindin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

CALB1 / Calbindin Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ CALB1 / Calbindin Antibody (aa3-261) for IHC, WB/Western LS-B16860 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 10/31/2024